Association of cardiac biomarkers with acute kidney injury after cardiac surgery: A multicenter cohort study Emilie P. Belley-Côté, MD, Chirag R. Parikh,

Slides:

Advertisements

Similar presentations

The Extent of Myocardial Injury During Prolonged Targeted Temperature Management After Out-of-Hospital Cardiac Arrest Anders Morten Grejs, MD, Jakob.

Advertisements

Manuel J. Antunes, MD, PhD, DSc

Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction:

Relationship between perioperative N-terminal pro-brain natriuretic peptide and maximum inotropic score in children after cardiac surgery Yanqin Cui,

Prediction of severe acute kidney injury after pediatric cardiac surgery with the use of novel biomarkers: A new trend in clinical research and risk stratification

30-Day Readmissions After an Acute Kidney Injury Hospitalization

Stephen D. Cassivi, MD, MSc, FRCSC, FACS

Christina A. de Fontnouvelle, BS, Jason H

The Extent of Myocardial Injury During Prolonged Targeted Temperature Management After Out-of-Hospital Cardiac Arrest Anders Morten Grejs, MD, Jakob.

Jeremiah R. Brown, PhD, MS, Robert S. Kramer, MD, Todd A

Plasma Monocyte Chemotactic Protein-1 Is Associated With Acute Kidney Injury and Death After Cardiac Operations Dennis G. Moledina, MBBS, Selin Isguven,

Prediction of acute kidney injury within 30 days of cardiac surgery

Process improvement in cardiac surgery: Development and implementation of a reoperation for bleeding checklist Gabriel Loor, MD, Alessandro Vivacqua,

Myocardial injury in coronary artery bypass grafting: On-pump versus off-pump comparison by measuring high-sensitivity C-reactive protein, cardiac troponin.

Intrinsic cardiac stem cells are essential for regeneration

Usman A. Khan, MD, Steven G. Coca, DO, MS, Kwangik Hong, MA, Jay L

Volume 80, Issue 6, Pages (September 2011)

Safety and efficacy of landiolol hydrochloride for prevention of atrial fibrillation after cardiac surgery in patients with left ventricular dysfunction:

Late remote ischemic preconditioning in children undergoing cardiopulmonary bypass: A randomized controlled trial Marcos A. Pavione, MD, Fabio Carmona,

Physical and mental recovery after conventional aortic valve surgery

Cutoff for high-sensitivity cardiac troponin T is not arbitrary but according to usual clinical practice Hector Cubero-Gallego, MD, PhD, Maria Heredia,

Cold blood cardioplegia reduces the increase in cardiac enzyme levels compared with cold crystalloid cardioplegia in patients undergoing aortic valve.

Risk-corrected impact of mechanical versus bioprosthetic valves on long-term mortality after aortic valve replacement Ole Lund, MD, PhD, Martin Bland,

One-year results of thoracic endovascular aortic repair for blunt thoracic aortic injury (RESCUE trial) Ali Khoynezhad, MD, PhD, FACS, Carlos E. Donayre,

The lord of the rings Antonio Miceli, MD, PhD

Conduit conundrum: If not two, why three?

Performance of the European System for Cardiac Operative Risk Evaluation II: A meta- analysis of 22 studies involving 145,592 cardiac surgery procedures

Early intraoperative iron-binding proteins are associated with acute kidney injury after cardiac surgery Nora Choi, MSc, Reid Whitlock, BSc, Jessica.

Benjamin G. Arenson, BSc, Lindsey A. MacDonald, BSc, Hilary P

Prophylactic nesiritide does not prevent dialysis or all-cause mortality in patients undergoing high-risk cardiac surgery A. Ahsan Ejaz, MD, Tomas D.

Innovation and science: The future of valve design

It's not “just a shunt” but sometimes it should be…

Fixing the supply problem

A first start for lung transplantation?

Combined Use of the Novel Biomarkers High-Sensitivity Troponin T and ST2 for Heart Failure Risk Stratification vs Conventional Assessment Josep Lupón,

Study Designs in Patient-Oriented Research

Yoan Lamarche, MD, Mahsa Elmi-Sarabi, MSc, Lillian Ding, MSc, James G

Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD

Chronic obstructive pulmonary disease severity influences outcomes after off-pump coronary artery bypass Benjamin Medalion, MD, Michael G. Katz, MD,

Fenton H. McCarthy, MD, MS, Nimesh D. Desai, MD, PhD

Niv Ad, MD, Lawrence M. Wei, MD

Daniel T. Engelman, MD, FACS, Michael J. Germain, MD

Sarah C. Huen, MD, Chirag R. Parikh, MD, PhD

Instrumental variable methods in clinical research

Attachment disorder in thoracoabdominal surgery

The Ross procedure: Time to reevaluate the guidelines

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Using bilateral internal thoracic arteries—just do it

Meyeon Park, MD, MAS, Michael G

The harder one looks, the more one finds

The impact of frailty on postoperative delirium in cardiac surgery patients Patrick Jung, BSc, Michael Ashley Pereira, BSc, Brett Hiebert, MSc, Xiaiwei.

Is single-dose prophylactic gentamicin associated with acute kidney injury in patients undergoing cardiac surgery? A matched-pair analysis Dorthe Viemose.

The origins of open heart surgery at the University of Minnesota 1951 to 1956 Richard A. DeWall, MD The Journal of Thoracic and Cardiovascular Surgery

Jeffrey H. Shuhaiber, MD, Jeff Moore, MS, David B. Dyke, MD

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

The future of cardiac surgery training: A survival guide

Commentary: “Isn't cardiac surgery a team sport?”

Apparently, size matters…in congenital heart disease and brain injury

Reliability of risk algorithms in predicting early and late operative outcomes in high-risk patients undergoing aortic valve replacement Todd M. Dewey,

Vinay Badhwar, MD, John S. Ikonomidis, MD, PhD, Jeffrey P. Jacobs, MD

“The more things change…”: The challenges ahead

Why arch curvature affects arch resistance

Commentary: Avoiding acute kidney injury after cardiac operations: Searching for the holy grail is not easy Victor A. Ferraris, MD, PhD The Journal.

Managing conflicts of interest

First in line for robotic surgery: Would you want to know?

Ryan R. Davies, MD The Journal of Thoracic and Cardiovascular Surgery

Of mice and men… The Journal of Thoracic and Cardiovascular Surgery

Did you like Terminator 3 better than Terminator 2

Journal changes and initiatives

Presentation transcript:

Association of cardiac biomarkers with acute kidney injury after cardiac surgery: A multicenter cohort study Emilie P. Belley-Côté, MD, Chirag R. Parikh, MD, PhD, Colleen R. Shortt, BSc, Steven G. Coca, DO, MS, Amit X. Garg, MD, PhD, MA, John W. Eikelboom, MD, MBBS, Peter Kavsak, PhD, Eric McArthur, MSc, Heather Thiessen-Philbrook, MMath, AStat, Richard P. Whitlock, MD, PhD Dr Prasad Devarajan, Dr Charles Edelstein, Dr Cary Passik, Dr Madhav Swaminathan, Dr Uptal Patel, Dr Michael Zappitelli, Dr Isabel Butrymowicz Emilie P. Belley-Côté, MD, Chirag R. Parikh, MD, PhD, Colleen R. Shortt, BSc, Steven G. Coca, DO, MS, Amit X. Garg, MD, PhD, MA, John W. Eikelboom, MD, MBBS, Peter Kavsak, PhD, Eric McArthur, MSc, Heather Thiessen-Philbrook, MMath, AStat, Richard P. Whitlock, MD, PhD Dr Prasad Devarajan, Dr Charles Edelstein, Dr Cary Passik, Dr Madhav Swaminathan, Dr Uptal Patel, Dr Michael Zappitelli, Dr Isabel Butrymowicz The Journal of Thoracic and Cardiovascular Surgery Volume 152, Issue 1, Pages 245-251.e4 (July 2016) DOI: 10.1016/j.jtcvs.2016.02.029 Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Study flow diagram. AKI, Acute kidney injury. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 245-251.e4DOI: (10.1016/j.jtcvs.2016.02.029) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Appendix E3 Boxplots of the perioperative cardiac biomarkers according to severe acute kidney injury. A, hs-cTnT. B, cTnI. C, CK-MB. D, NT-proBNP. The patients who developed the events are represented in red. The patients free of events are in blue. Day 1 samples were collected within 6 hours of surgery. Horizontal line is the median, and box extends from the 25th to 75th percentile. AKI, Acute kidney injury; CK-MB, creatine kinase-MB; NT-proBNP, N-terminal prohormone of brain natriuretic peptide. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 245-251.e4DOI: (10.1016/j.jtcvs.2016.02.029) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Appendix E9 A, Kaplan–Meier curve: association between highest measured high-sensitivity troponin T tertiles and long-term mortality. B, Kaplan–Meier curve: association between highest measured cardiac troponin I tertiles and long-term mortality. C, Kaplan–Meier curve: association between highest measured creatine kinase-MB tertiles and long-term mortality. D, Kaplan–Meier curve: association between highest measured N-terminal prohormone of brain natriuretic peptide tertiles and long-term mortality. CK-MB, Creatine kinase-MB; NT-proBNP, N-terminal prohormone of brain natriuretic peptide. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 245-251.e4DOI: (10.1016/j.jtcvs.2016.02.029) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

Association between highest measured NT-proBNP tertiles and long-term mortality. The Journal of Thoracic and Cardiovascular Surgery 2016 152, 245-251.e4DOI: (10.1016/j.jtcvs.2016.02.029) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions