Volume 27, Issue 13, Pages e7 (July 2017)

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Volume 27, Issue 13, Pages 2023-2028.e7 (July 2017) Eight Millennia of Matrilineal Genetic Continuity in the South Caucasus  Ashot Margaryan, Miroslava Derenko, Hrant Hovhannisyan, Boris Malyarchuk, Rasmus Heller, Zaruhi Khachatryan, Pavel Avetisyan, Ruben Badalyan, Arsen Bobokhyan, Varduhi Melikyan, Gagik Sargsyan, Ashot Piliposyan, Hakob Simonyan, Ruzan Mkrtchyan, Galina Denisova, Levon Yepiskoposyan, Eske Willerslev, Morten E. Allentoft  Current Biology  Volume 27, Issue 13, Pages 2023-2028.e7 (July 2017) DOI: 10.1016/j.cub.2017.05.087 Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 1 Study Area Maps of the Near East (insert) and Armenia with sampling and origin areas of ancient and modern individuals, respectively. The legend shows the number of samples and the approximate time period covered by each cultural group. EBA, early Bronze Age; MBA, middle Bronze Age; LBA, late Bronze Age; EIA, early Iron Age; LIA, late Iron Age. See also Table S1. Current Biology 2017 27, 2023-2028.e7DOI: (10.1016/j.cub.2017.05.087) Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 2 mtDNA Haplogroups The figure shows the modern groups including three Armenian (Ararat, Artsakh, and Erzrum), Central Asian (Tajikistan, Kyrgyzstan, and Uzbekistan combined), and European (Italy-Tuscany, Poland, and Bulgaria combined) populations. “Other” denotes the combined frequencies of mtDNA haplogroups with less than 1% in Europe and Central Asia. Extended haplogroup frequencies and references for the European and Central Asian populations are presented in the Table S4. See also Data S1, Figure S1 as well as Tables S2 and S3. Current Biology 2017 27, 2023-2028.e7DOI: (10.1016/j.cub.2017.05.087) Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 3 MDS Plot The MDS analysis was based on FST genetic distances using whole mtDNA sequences of the ancient group (blue), modern Armenians (blue), and neighboring populations from the Near East and the South Caucasus (green). See also Table S5 and Figure S2. Current Biology 2017 27, 2023-2028.e7DOI: (10.1016/j.cub.2017.05.087) Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 4 Population Demographics (A) Bayesian skyline plot. Values on the y axis represent the effective female population size (Ne) × generation time (g). (B) Schematic representation of the five demographic models used for coalescent ABC simulations. Population sizes of modern Armenians (NM), ancient group (NA), “ghost” Asian population (NG), first bottleneck (20 kya; NB), second bottleneck (40 kya; Nb) are shown. For the details of ABC analysis and rationale behind the model choices, see STAR Methods. See also Table S3. Current Biology 2017 27, 2023-2028.e7DOI: (10.1016/j.cub.2017.05.087) Copyright © 2017 Elsevier Ltd Terms and Conditions