Diphtheria.

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Presentation transcript:

Diphtheria

Pathogenesis Corynebacterium diphtheriae infected with toxinogenic bacteriophage http://www.microbiologyinpictures.com/bacteria%20photos/corynebacterium%20diphtheriae%20photos/CODI18.html

A-B toxin http://brainboxes2.wikispaces.com/file/view/diphtheria_toxin_mechanism.gif/279097328/502x827/diphtheria_toxin_mechanism.gif

Signs and Symptoms Early Stage Sore throat Fever Fatigue Late Stage Gray pseudomembrane “Bull-neck” Breathing difficulties Croup-like cough Skin lesions http://www.nlm.nih.gov/medlineplus/ency/article/001608.htm http://www.medlink.com/medlinkcontent.asp

http://www. atmph. org/viewimage. asp http://www.atmph.org/viewimage.asp?img=AnnTropMedPublicHealth_2012_5_4_302_102031_b3.jpg

Treatment Antitoxin Antibiotics: erythromycin

Prevention Toxoid vaccine

Epidemiology http://www.who.int/immunization/monitoring_surveillance/burden/vpd/surveillance_type/passive/diphtheria/en/

http://www.dipnet.org/general.public.php

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