Data Triumph at C Cancer Cell Mark Levine, Pierre-Christian Violet Cancer Cell Volume 31, Issue 4, Pages 467-469 (April 2017) DOI: 10.1016/j.ccell.2017.03.008 Copyright © 2017 Terms and Conditions
Figure 1 Pharmacologic Ascorbate Mediation of Cancer Cell Death Pharmacologic ascorbate is a pro-drug for formation of extracellular H2O2. H2O2 diffuses intracellularly and interacts with iron or other metal centers to form reactive oxygen species (ROS). ROS modulate multiple downstream pathways and targets that induce cancer cell death. Cancer Cell 2017 31, 467-469DOI: (10.1016/j.ccell.2017.03.008) Copyright © 2017 Terms and Conditions