by Keren Mizrahi, and Nadir Askenasy

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by Keren Mizrahi, and Nadir Askenasy Physiological functions of TNF family receptor/ligand interactions in hematopoiesis and transplantation by Keren Mizrahi, and Nadir Askenasy Blood Volume 124(2):176-183 July 10, 2014 ©2014 by American Society of Hematology

Interactions between TNF family receptors. Interactions between TNF family receptors. (A) Stem and progenitor cells; (B) the differentiated progeny. The impact of receptor ligation by the cognate ligands and crosstalk are presented in reference to proliferation, induced expression, apoptosis, survival, and trophic signaling. Joint activation of Fas/TNF-R1 and Fas/TRAIL-R1 results in superior survival, with dominant influence of the TNFα and TRAIL receptors. Keren Mizrahi, and Nadir Askenasy Blood 2014;124:176-183 ©2014 by American Society of Hematology