Evaluation of published single nucleotide polymorphisms associated with acute GVHD by Jason W. Chien, Xinyi Cindy Zhang, Wenhong Fan, Hongwei Wang, Lue.

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Evaluation of published single nucleotide polymorphisms associated with acute GVHD by Jason W. Chien, Xinyi Cindy Zhang, Wenhong Fan, Hongwei Wang, Lue Ping Zhao, Paul J. Martin, Barry E. Storer, Michael Boeckh, Edus H. Warren, and John A. Hansen Blood Volume 119(22):5311-5319 May 31, 2012 ©2012 by American Society of Hematology

Candidate SNP genotype determination algorithm. Candidate SNP genotype determination algorithm. HWE indicates Hardy-Weinberg equilibrium; MAF, minor allele frequency; and SNP, single-nucleotide polymorphism. Jason W. Chien et al. Blood 2012;119:5311-5319 ©2012 by American Society of Hematology

Forest plots for unadjusted and adjusted analyses of aGVHD and candidate SNPs. Forest plots for unadjusted (squares) and adjusted (circles) analyses of aGVHD and candidate SNPs among MRD (A) and URD (B) HCT. Hazard ratios are represented on the x-axis in lo... Forest plots for unadjusted and adjusted analyses of aGVHD and candidate SNPs. Forest plots for unadjusted (squares) and adjusted (circles) analyses of aGVHD and candidate SNPs among MRD (A) and URD (B) HCT. Hazard ratios are represented on the x-axis in logarithmic scale. Positive values indicate an increased risk for aGVHD, and negative values indicate a decreased risk for aGVHD. Gene/rs numbers in bold and closed squares and circles indicate the association exceeded the P = .05 threshold. Jason W. Chien et al. Blood 2012;119:5311-5319 ©2012 by American Society of Hematology