The STENT Thrombosis Study 10,000 consecutive patients receiving DES at up to 12 sites Aspirin and clopidogrel responsiveness evaluated Using the Accumetrics VerifyNow system Clinical Follow-Up for 2-5 years Angiographic core lab assessment of all stent thromboses and 1:3 matching controls Supported by grants from Boston Scientific (lead contributor), Accumetrics, Abbott Vascular, Cordis, and Medtronic Presented at TCT 2006

The E-Select Registry and INSIGHT Randomized Trial 30,000 patient global registry + U.S. randomized trial of standard vs. long duration clopidogrel Sponsor: Cordis Corp. The PROTECT Randomized Trial 8,000 patient global randomized trial of the Endeavor vs. the Cypher stent. Primary Endpoint = stent thrombosis Sponsor: Medtronic Corp. Presented at TCT 2006