Moving Further with Medical Tailoring

Slides:



Advertisements
Similar presentations
When Should a Clinical Trial Design with Pre-Stratification be Used? Group 1.
Advertisements

Multilevel Interventions: Study Design and Analysis Issues Paul D. Cleary, Ph.D. Yale School of Public Health Cary Gross, M.D. Yale School of Medicine.
Clinical Trial Designs for the Evaluation of Prognostic & Predictive Classifiers Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer.
Sino-Danish Breast Cancer Research Centre Beijing Genomic Institute, Shenzhen University of Copenhagen University of Århus University of Southern Denmark.
Research Grant/Fund Opportunity for Nursing in Taiwan.
Personalized Medicine Presentation by: Alex Wiki by: John and Lydia.
American Evaluation Association EVALUATION 2011 November 3, 2011 Approaches to Biomedical Research and Development Portfolio Analysis: Examples From the.
3 rd Summer School in Computational Biology September 10, 2014 Frank Emmert-Streib & Salissou Moutari Computational Biology and Machine Learning Laboratory.
Genetic Testing in Genomic Medicine Gail H. Vance M.D. Professor, Department of Medical & Molecular Genetics Indiana University School of Medicine.
Breast cancer and medical second opinion
Precision Medicine: From stratified therapies to personalized therapies Fabrice ANDRE Institut Gustave Roussy Villejuif, France.
The All Breast Cancer Report was published in October breastscreen/research.html#breast- cancer-report.
Driving the Transition to Individualized Cancer Treatment by Addressing Critical Questions 1 Do I need surgery? chemotherapy? radiation? INVASIVE BREAST.
Molecular Biomarkers in Radiotherapy of Cervical Cancer A collaboration project between Department of Gynecologic Oncology and Department of Radiation.
©2009 RALPH SNYDERMAN 1 Personalized Health Care: The Foundation of Rational Health Reform Ralph Snyderman, MD Chancellor Emeritus, Duke University James.
Therapeutic Education: Cancer Patients on chemotherapy: Shamim Akhter QURESHI MBBS,MPH, Ingénieur d’étude(EHESP) 2 nd June 2012 June 2010.
Surrogate Endpoints and Correlative Outcomes Hem/Onc Journal Club January 9, 2009.
2010 NIAMS Scientific Retreat Comparative Effectiveness Research Institute of Medicine Priorities Functional Limitations & Disabilities Endocrinology &
Where to focus? Horizon 2020 'Health, demographic change and wellbeing' Open Info Day -Horizon 2020 'Health, demographic change and wellbeing' Brussels,
Low-molecular-weight heparin (LMWH) use in an oncological setting Emma Lowe, Melanie Lowe, Hilary Oldham, Joan Karasu. Clinical service technicians, Pharmacy.
Medical Informatics Workshop Prognostic Matches and Mismatches HIS: Medical Knowledge and Decision Support (T20-T21) Casimir Kulikowski and Rainer.
BY Nisvil Smith.  Nuclear medicine is a branch of medical imaging that uses small amounts of radioactive material to diagnose and determine the severity.
OMICS Group Contact us at: OMICS Group International through its Open Access Initiative is committed to make genuine and.
Mental Health Services, University of Copenhagen 1.
Breast Cancer in Ghana How are we going to ‘beat’ it? Prof J-N Clegg-Lamptey SAMF Launch.
WERKGROEP HERSENTUMOREN vzw Study Group Brain Tumours RECENT ADVANCES IN THE BRAIN IMAGING A PATIENTS OPINION European Parliament, Brussels.
Mesothelioma Nasty form of cancer Attributed to inhalation of asbestos fibers People who worked with or near asbestos typically at most risk.
Full Proposal for the German Cancer Aid Priority Program 'Translational Oncology' (2st call) 2015 Lead Applicants: Prof. Dr. med. Magnus von Knebel Doeberitz.
National Cancer Intelligence Network Outcome and the effect of age in 1318 patients with synovial sarcoma: Report from the National Cancer Intelligence.
1 Trends in drug development programs in the era of Personalized Medicine Gunnar Saeter, M.D., Ph.D. Head, Institute for Cancer Research Oslo University.
Genomic Medicine Rebecca Tay Oncology Registrar. What is Genomic Medicine? personalised, precision or stratified medicine.
Medical and Health research in Norway – in brief Director Mari K. Nes 22 June 2006.
RECTAL CARCINOMA AND PREOPERATIVE MRI: USING A NATIONAL DATASET FOR REGIONAL AUDIT South West Cancer Intelligence Service J Weeks
Within the Cancer Program in MUH doing the best research and providing the best care to our patients. This is the best cancer care hospital.cancer care.
Point of Care Testing for Personalised Medicine and Health
Palliative Care in MND Barry Laird Clinician Scientist in Palliative Medicine, University of Edinburgh and PRC Consultant in Palliative Medicine, St Columba’s.
PH-ELIM Kick-Off-Meeting Medical Informatics at the
Fig. 1 Frequency distribution of initial palliative treatment modalities used. EBRT, external beam radiotherapy. Initial palliative treatment modality.
NCT: Gaining Medical Insights and Enhancing Care for Cancer Patients with SAP HANA® Organization National Center for Tumor Diseases (NCT) Heidelberg, part.
Pharmacogenomics: towards personalized medicine
Big Data Analyses: The Cancer Moonshot
Specialist of Clinical pathology Patient safety officer
Analysis of referral patterns and regional neuro-oncology multi-disciplinary team decisions in brain metastasis Dr Kamalram THIPPU JAYAPRAKASH, Dr Javier.
Data-Drive Analytics for Precision Medicine
Introduction. TREATMENT BASED ON TUMOR SIDEDNESS IN mCRC: THE EVIDENCE AND PRACTICAL APPLICATION.
CSS Clinical Trial Launched: January 2018
Finland, a Global Testbed for Personalized Cancer Research?
A Paradigm Shift From One-Size-Fits-All to Tailor-Made Therapy for Metastatic Colorectal Cancer.
The Genomics of Cancer and Molecular Testing:
West of England Genomics Medicine Centre Overview
Dynamic Risk Stratification in ACS
A. Dix, S. Vlaic, R. Guthke, J. Linde 
Future Health Outlook April 23, 2018.
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro
Why study Brain tumour Biology???
Fig. 1. scRNA-seq applications in cancer medicine.
Patient-Centered Management in Advanced Non-Small Cell Lung Cancer
Precision Medicine A New Era Hazem Assi American University of Beirut
Nat. Rev. Urol. doi: /nrurol
Figure 2 Sources of data to characterize the ADPKD clinical phenotype
Figure 3 Enrichment strategies for clinical trials
Volume 151, Issue 4, Pages (October 2016)
Surveillance of intestinal colonization and of infection by vancomycin-resistant enterococci in hospitalized cancer patients  Florence Moulin, Sandrine.
Genomics BioSci. & Tech., SME Located in Taipei city.
The 3rd Stat4Onc Annual Symposium
Figure 3 Determination of the primary site
Secular trends in mortality associated with bloodstream infections in 4268 patients hospitalized in a cancer referral left between 1975 and 1989  Antoine.
MSI.
Single-cell analyses to tailor treatments
Vylyny Chat, Robert Ferguson, Tomas Kirchhoff 
Presentation transcript:

Moving Further with Medical Tailoring ”Personalized Medicine” ”Precision Medicine” ”Tailored Medicine” Gunnar Sæter Institute for Cancer Research Oslo University Hospital

“A practice where medical decisions and interventions are tailored to the individual patient´s constitutive or specific disease (molecular) characteristics”

Cancer Rare Heritable Diseases A Infectious Diseases A Severe Mental Disorders Individual approaches

Predictive biomarkers Data integration/”Big Data” The Cancer Treatment Pillars Surgery Radiotherapy Chemotherapy Prognostic factors Predictive biomarkers Multiple parameters Bioinformatics Data integration/”Big Data” Precision Medicine Tumour based biomarkers ”Multi-Omics” Immunotherapy Tumour & host based biomarkers Se i sammenheng med CCC

MAIN SESSION 1: MOVING TREATMENT FURTHER WITH PERSONALIZED MEDICINE Personalized Medicine - A true paradigm shift? Alexander Eggermont, Institut Gustave Roussy, Paris Do we see the practical consequences of clinical implementation? Per Eystein Lønning, Haukeland University Hospital/University of Bergen Do we have the technology and availability needed for clinical implementation? Hege Russnes, Oslo University Hospital