Russell D. Hull, MBBS, MSc, Jane Liang, MSc, Grace Townshend, MSc

Slides:

Advertisements

Similar presentations

Low-Dose Aspirin in Patients with Stable Cardiovascular Disease: A Meta-analysis Jeffrey S. Berger, MD, MS, David L. Brown, MD, Richard C. Becker, MD The.

Advertisements

Paul D. Stein, MD, Fadi Matta, MD, Mary J. Hughes, DO

The Effect of Smoking on the Risk of Sciatica: A Meta-analysis

Long-term Low-Molecular-Weight Heparin versus Usual Care in Proximal-Vein Thrombosis Patients with Cancer Russell D. Hull, MBBS, MSc, Graham F. Pineo,

Russell D. Hull, MBBS, MSc, Graham F. Pineo, MD, Rollin F

Stuart A. Ross, MB CHB, FRACP, FRCP(C)

Alternative Smoking Cessation Aids: A Meta-analysis of Randomized Controlled Trials Mehdi Tahiri, MD, Salvatore Mottillo, MD, Lawrence Joseph, PhD, Louise.

Ahmed Abuzaid, MD, Carly Fabrizio, DO, Kevin Felpel, MD, Haitham S

An Unusual Cause of Leg Ulcerations

Duration of Dual Antiplatelet Therapy in Patients with an Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Chirag Bavishi, MD, MPH,

Impact of More Restrictive Blood Transfusion Strategies on Clinical Outcomes: A Meta- analysis and Systematic Review Shelley R. Salpeter, MD, Jacob S.

Alexander A. Leung, MD, MPH, Finlay A. McAlister, MD, MSc, Samuel R. G

James H. Liu, MD The American Journal of Medicine

Paul D. Stein, MD, Russell D. Hull, MBBS, MSc, Fadi Matta, MD, Abdo Y

Alternative Smoking Cessation Aids: A Meta-analysis of Randomized Controlled Trials Mehdi Tahiri, MD, Salvatore Mottillo, MD, Lawrence Joseph, PhD, Louise.

Samy Suissa, PhD, Abbas Kezouh, PhD, Pierre Ernst, MD, MSc

Maureen M. Okam, MD, MPH, Todd A. Koch, Minh-Ha Tran, DO

Systematic Review of the Mediterranean Diet for Long-Term Weight Loss

Systematic Review and Meta-analysis of Adverse Events of Low-dose Aspirin and Clopidogrel in Randomized Controlled Trials Kenneth R. McQuaid, MD, Loren.

Low molecular weight heparin versus oral anticoagulants in the long-term treatment of deep venous thrombosis Paloma López-Beret, MD, Antonio Orgaz, MD,

Net Clinical Benefit of Non-vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Phase III Atrial Fibrillation Trials Giulia Renda, MD, PhD, Marta.

Effect of Aspirin on Mortality in the Primary Prevention of Cardiovascular Disease Nina Raju, MD, MsC, Magdalena Sobieraj-Teague, MBBS, Jack Hirsh, MD,

Thomas E. MacMillan, MD, MSc, Terence Tang, MD, Rodrigo B

Epidemiology of Myelodysplastic Syndromes

A Randomized, Double-Blind, Placebo-Controlled Trial of Nutritional Supplementation During Acute Illness Salah Gariballa, MD, Sarah Forster, MSc, Stephen.

Use of Targeted Temperature Management After Out-of-hospital Cardiac Arrest: A Meta- Analysis of Randomized Controlled Trials Ahmed Mahmoud, MD, Islam.

Impetigo-like vegetating nasal lesions caused by Klebsiella pneumoniae

Long-term Low-Molecular-Weight Heparin versus Usual Care in Proximal-Vein Thrombosis Patients with Cancer Russell D. Hull, MBBS, MSc, Graham F. Pineo,

Russell D. Hull, MBBS, MSc, Graham F. Pineo, MD, Rollin F

Baffling Tachycardia The American Journal of Medicine

Robert Goulden, MBBS, MSc, MPhil, MA The American Journal of Medicine

Sabina Hunziker, MD, MPH, Jennifer Stevens, MD, MS, Michael D

Ranjita Pallavi, MD, Shobhana Chaudhari, MD

Muhammad Amer, MD, MHS, FACP, Rehan Qayyum, MD, MHS

Painless Horner's Syndrome Through Occupational Exposure

Michael A. Pfaller, MD The American Journal of Medicine

The Reply The American Journal of Medicine

TIA for the Internist The American Journal of Medicine

Hong-Tao Tie, MD, Rui Shi, MD The American Journal of Medicine

Diagnostic and Therapeutic Yield of Endoscopy in Patients with Elevated INR and Gastrointestinal Bleeding Joanna M. Peloquin, MD, Siamak M. Seraj, MD,

Jan C. van Blijderveen, MSc, MD, Sabine M. Straus, PhD, MD, Eline M

Gout in African Americans

Treatment of hepatitis C

Cardiovascular Risks of Exogenous Testosterone Use Among Men: A Systematic Review and Meta-Analysis G. Caleb Alexander, MD, MS, Geetha Iyer, MBBS, Eleanor.

An Enlarging Ulcer The American Journal of Medicine

Carlos Aguilar, MD, Valentin del Villar, MD

Evaluation of the HAS-BLED, ATRIA, and ORBIT Bleeding Risk Scores in Patients with Atrial Fibrillation Taking Warfarin Keitaro Senoo, MD, Marco Proietti,

Isla M. Ogilvie, PhD, Nick Newton, PhD, Sharon A

Fusobacterium nucleatum Bacteremia Presenting with Portal Vein Thrombosis: An Abdominal Lemierre Syndrome? Joseph A. Moore, MD, Siayareh Rambally, MD

Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?

Clinical Outcomes After Treatment of Cocaine-Induced Chest Pain with Beta-Blockers: A Systematic Review and Meta-Analysis Kevin Bryan Lo, MD, Hafeez.

Usefulness of CHADS2 and CHA2DS2-VASc Scores in the Prediction of New-Onset Atrial Fibrillation: A Population-Based Study Walid Saliba, MD, MPH, Naomi.

Prevalence and Risk Factors for Erectile Dysfunction in the US

Insomnia in the Elderly: Cause, Approach, and Treatment

Age Differences in Treatment and Control of Hypertension in US Physician Offices, : A Serial Cross-sectional Study Anna Gu, MD, PhD, Yu Yue,

Ahmed Abuzaid, MD, Carly Fabrizio, DO, Kevin Felpel, MD, Haitham S

One-way Versus Two-way Text Messaging on Improving Medication Adherence: Meta- analysis of Randomized Trials David S. Wald, MD, FRCP, Shahena Butt, MSc,

Purple Urinary Bag Syndrome

National Trends in Ambulatory Oral Anticoagulant Use

A Post-cure Complication

Risk of Falls and Major Bleeds in Patients on Oral Anticoagulation Therapy Jacques Donzé, MD, MSc, Carole Clair, MSc, MD, Balthasar Hug, MD, MBA, MPH,

Combining Antiplatelet and Antithrombotic Therapy (Triple Therapy): What Are the Risks and Benefits? Luis Alejandro Asencio, MD, Jennifer J. Huang, DO,

Is Salt a Culprit or an Innocent Bystander in Hypertension

The Economic Burden of Hyponatremia: Systematic Review and Meta-Analysis Giovanni Corona, MD, PhD, Corinna Giuliani, MD, Gabriele Parenti, MD, PhD, Giorgio.

The Reply The American Journal of Medicine

Falls in Older Adults: Risk Assessment, Management and Prevention

Has mortality from acute renal failure decreased

Toward a More Responsible News Media

David Tian, MD, Ram Jhingan Mohan, MD, Gary Stallings, MD

Jay S. Kaufman, PhD, Sam Harper, PhD The American Journal of Medicine

Presentation transcript:

Long-term Low-Molecular-Weight Heparin and the Post-Thrombotic Syndrome: A Systematic Review Russell D. Hull, MBBS, MSc, Jane Liang, MSc, Grace Townshend, MSc The American Journal of Medicine Volume 124, Issue 8, Pages 756-765 (August 2011) DOI: 10.1016/j.amjmed.2011.02.033 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Risk ratios for the (A) presence of venous ulcers and (B) absence of complete recanalization of thrombosed veins or complete lysis of thrombus, after treatment with long-term low-molecular-weight heparin or oral anticoagulation. A ratio of < 1 favors tinzaparin. Both were calculated using a fixed-effect model. For ulcers: Daskalopoulos et al's trial:24 6-mo therapy with tinzaparin and follow-up at 1 y; Hull et al's study:11 3-mo therapy with tinzaparin and follow-up at 3 mo. For recanalization: Values are those reported for follow-up at 6 mo for Romera et al19 and 3 mo for all the other studies. For López-Beret et al,26 values reported for the popliteal vein were used. Values for the common and superficial femoral veins would have favored low-molecular-weight heparin to an even greater extent (Table 3). CI = confidence interval; LMWH = low-molecular-weight heparin; OA = oral anticoagulant. The American Journal of Medicine 2011 124, 756-765DOI: (10.1016/j.amjmed.2011.02.033) Copyright © 2011 Elsevier Inc. Terms and Conditions