Volume 152, Issue 3, Pages e5 (February 2017)

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Volume 152, Issue 3, Pages 648-664.e5 (February 2017) American Gastroenterological Association Institute Technical Review on Initial Testing and Management of Acute Liver Disease Steven K. Herrine, Paul Moayyedi, Robert S. Brown, Yngve T. Falck-Ytter Gastroenterology Volume 152, Issue 3, Pages 648-664.e5 (February 2017) DOI: 10.1053/j.gastro.2016.12.027 Copyright © 2017 AGA Institute Terms and Conditions

Figure 1 Hierarchical summary receiver-operator curves (HSROC) from all studies that evaluated KCC and MELD with mortality as the outcome. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Figure 2 Forest plot of randomized trials of the effect of extracorporeal liver support systems vs usual care on mortality. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Figure 3 Forest plot of randomized trials of the effect of N-acetyl cysteine vs placebo on mortality. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 1 Forest plot of the proportion of cases of acute liver failure in pregnant women that were caused by hepatitis E virus. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 2 Forest plot of odds ratio of having HEV-associated ALF in pregnant vs nonpregnant women. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 3 Forest plot of the mortality rate of HEV-associated ALF in pregnancy. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 4 Forest plot of the effects of interventions to reduce intracranial pressure vs placebo/usual care in reducing mortality in acute liver failure. M-H, Mantel-Haenszel. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 5 Forest plot of extracorporeal liver support systems vs usual care subgrouped into acute liver failure vs acute-on-chronic liver failure. M-H, Mantel-Haenszel. Gastroenterology 2017 152, 648-664.e5DOI: (10.1053/j.gastro.2016.12.027) Copyright © 2017 AGA Institute Terms and Conditions