The Association Between Autonomic Dysfunction and Survival in Male Patients with Advanced Cancer: A Preliminary Report Nada Fadul, MD, Florian Strasser,

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The Association Between Autonomic Dysfunction and Survival in Male Patients with Advanced Cancer: A Preliminary Report Nada Fadul, MD, Florian Strasser, MD, J. Lynn Palmer, PhD, Syed Wamique Yusuf, MD, Ying Guo, MD, Zhijun Li, MS, Julio Allo, MPH, Eduardo Bruera, MD Journal of Pain and Symptom Management Volume 39, Issue 2, Pages 283-290 (February 2010) DOI: 10.1016/j.jpainsymman.2009.06.014 Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Survival associations of Ewing and heart rate variability tests. a) Ewing=Ewing autonomic test (0–5); b) SDNN=standard deviation of normal to normal beat interval in milliseconds; c) high=high-frequency power in millisecond2 (measure of parasympathetic function); d) low=low-frequency power in millisecond2 (measure of sympathetic function); e) very low=very-low-frequency power in millisecond2 (measure of sympathetic function). Journal of Pain and Symptom Management 2010 39, 283-290DOI: (10.1016/j.jpainsymman.2009.06.014) Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Kaplan-Meier curve for survival in patients with and without autonomic dysfunction (AD). AD is present if Ewing score is >2. Journal of Pain and Symptom Management 2010 39, 283-290DOI: (10.1016/j.jpainsymman.2009.06.014) Copyright © 2010 U.S. Cancer Pain Relief Committee Terms and Conditions