Volume 91, Issue 3, Pages (March 2017)

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Presentation transcript:

Volume 91, Issue 3, Pages 711-719 (March 2017) Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease Jair Munoz Mendoza, Tamara Isakova, Xuan Cai, Liz Y. Bayes, Christian Faul, Julia J. Scialla, James P. Lash, Jing Chen, Jiang He, Sankar Navaneethan, Lavinia Negrea, Sylvia E. Rosas, Matthias Kretzler, Lisa Nessel, Dawei Xie, Amanda Hyre Anderson, Dominic S. Raj, Myles Wolf Lawrence J. Appel, MD, MPH, Harold I. Feldman, MD, MSCE, Alan S. Go, MD, Jiang He, MD, PhD, John W. Kusek, PhD, James P. Lash, MD, Akinlolu Ojo, MD, PhD, Raymond R. Townsend, MD Jair Munoz Mendoza, Tamara Isakova, Xuan Cai, Liz Y. Bayes, Christian Faul, Julia J. Scialla, James P. Lash, Jing Chen, Jiang He, Sankar Navaneethan, Lavinia Negrea, Sylvia E. Rosas, Matthias Kretzler, Lisa Nessel, Dawei Xie, Amanda Hyre Anderson, Dominic S. Raj, Myles Wolf Lawrence J. Appel, MD, MPH, Harold I. Feldman, MD, MSCE, Alan S. Go, MD, Jiang He, MD, PhD, John W. Kusek, PhD, James P. Lash, MD, Akinlolu Ojo, MD, PhD, Raymond R. Townsend, MD Kidney International Volume 91, Issue 3, Pages 711-719 (March 2017) DOI: 10.1016/j.kint.2016.10.021 Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 1 Kaplan-Meier analysis of cumulative incidence of mortality according to quartiles of inflammatory markers. (a) interleukin (IL)-6; (b) C-reactive protein (CRP). Kidney International 2017 91, 711-719DOI: (10.1016/j.kint.2016.10.021) Copyright © 2016 International Society of Nephrology Terms and Conditions

Figure 2 Additive effects of elevated levels of inflammatory markers and fibroblast growth factor 23 (FGF23) on risk of mortality. Crude mortality rates according to (a) combined quartiles of interleukin (IL)-6 and FGF23 and (b) baseline quartiles (Q) of C-reactive protein and FGF23. Kidney International 2017 91, 711-719DOI: (10.1016/j.kint.2016.10.021) Copyright © 2016 International Society of Nephrology Terms and Conditions