Testosterone-Secreting Adrenal Adenoma That Contained Crystalloids of Reinke in an Adult Female Patient John J. Ryan, M.B., B.CH., Maher A. Rezkalla,

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Presentation transcript:

Testosterone-Secreting Adrenal Adenoma That Contained Crystalloids of Reinke in an Adult Female Patient John J. Ryan, M.B., B.CH., Maher A. Rezkalla, M.B., B.CH., Samir N. Rizk, M.B., B.Ch, K. Greg Peterson, M.D., R. Herbert Wiebe, M.D. Mayo Clinic Proceedings Volume 70, Issue 4, Pages 380-383 (April 1995) DOI: 10.4065/70.4.380 Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Photomicrograph, showing adrenal adenoma with typical cytoplasmic inclusions. (Hematoxylin-eosin; original magnification, ×200.) Mayo Clinic Proceedings 1995 70, 380-383DOI: (10.4065/70.4.380) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 2 Photomicrograph, showing adrenal adenoma cells with intracytoplasmic slender rod-shaped structures characteristic of Reinke's crystals. Leydig cells are arranged in sheets and solid cords of eosinophilic cells with large, centrally placed nuclei. (Hematoxylin-eosin; original magnification, ×400.) Mayo Clinic Proceedings 1995 70, 380-383DOI: (10.4065/70.4.380) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 3 Electron micrograph of salvaged paraffin-embedded tissue, showing poorly preserved tissue with intracytoplasmic crystals resembling hexagonal prisms characteristic of Reinke's crystals. Reinke's crystals are considered pathognomonic for identification of ovarian hilus cells and Leydig (hilus) cell tumors.15 (Original magnification, ×3,420.) Mayo Clinic Proceedings 1995 70, 380-383DOI: (10.4065/70.4.380) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions