Green-Red Flashers to Accelerate Biology

Slides:

Advertisements

Similar presentations

Halogen Bonds Form the Basis for Selective P-TEFb Inhibition by DRB Sonja Baumli, Jane A. Endicott, Louise N. Johnson Chemistry & Biology Volume 17, Issue.

Advertisements

Development of Antibiotic Activity Profile Screening for the Classification and Discovery of Natural Product Antibiotics Weng Ruh Wong, Allen G. Oliver,

Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis John Hines, Michael Groll, Margaret Fahnestock, Craig M. Crews Chemistry &

Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis Tim J. Wigle, Laurel M. Provencher, Jacqueline.

In Vivo Photoswitchable Flow Cytometry for Direct Tracking of Single Circulating Tumor Cells Dmitry A. Nedosekin, Vladislav V. Verkhusha, Alexander V.

Biocompatible Quantum Dots for Biological Applications Sandra J. Rosenthal, Jerry C. Chang, Oleg Kovtun, James R. McBride, Ian D. Tomlinson Chemistry &

Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates Bradley Croy Doak, Bj ӧ rn Over, Fabrizio Giordanetto, Jan Kihlberg.

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs Yves Pommier, Elisabetta Leo, HongLiang Zhang, Christophe Marchand Chemistry.

Proteasome Inhibitors: An Expanding Army Attacking a Unique Target Alexei F. Kisselev, Wouter A. van der Linden, Herman S. Overkleeft Chemistry & Biology.

Hoiamide A, a Sodium Channel Activator of Unusual Architecture from a Consortium of Two Papua New Guinea Cyanobacteria Alban Pereira, Zhengyu Cao, Thomas.

Context-Specific Target Definition in Influenza A Virus Hemagglutinin-Glycan Receptor Interactions Zachary Shriver, Rahul Raman, Karthik Viswanathan, Ram.

Staphylococcus aureus and Bacillus subtilis W23 Make Polyribitol Wall Teichoic Acids Using Different Enzymatic Pathways Stephanie Brown, Timothy Meredith,

LDAI-Based Chemical Labeling of Intact Membrane Proteins and Its Pulse-Chase Analysis under Live Cell Conditions Takayuki Miki, Sho-hei Fujishima, Kazuhiro.

The Efficacy of siRNAs against Hepatitis C Virus Is Strongly Influenced by Structure and Target Site Accessibility Selena M. Sagan, Neda Nasheri, Christian.

Cationic Fullerenes Are Effective and Selective Antimicrobial Photosensitizers George P. Tegos, Tatiana N. Demidova, Dennisse Arcila-Lopez, Haeryeon Lee,

Glycosidase Inhibition by Macrolide Antibiotics Elucidated by STD-NMR Spectroscopy Ali Sadeghi-Khomami, Michael D. Lumsden, David L. Jakeman Chemistry.

D. Grahame Hardie, Fiona A. Ross, Simon A. Hawley Chemistry & Biology

Nucleosomes and Cisplatin

Volume 22, Issue 5, Pages v-vi (May 2015)

Now Playing: Farnesol in the Biofilm

Volume 27, Issue 11, Pages R447-R448 (June 2017)

Enzyme Annotation with Chemical Tools

New Light on Methylthiolation Reactions

Tailor-Made Peptide Synthetases

Laminopathies: Too Much SUN Is a Bad Thing

Nucleosomes and Cisplatin

On-Bead Library Screening Made Easier

Antibiotics: A New Hope

Foundations for Directed Alkaloid Biosynthesis

Ribosome Evolution for Two Artificial Amino Acids in E. coli

Nature’s Strategy for Catalyzing Diels-Alder Reaction

Scratch n’ Screen for Inhibitors of Cell Migration

Chemical Proteomics of Host-Pathogen Interaction

The future's bright: Imaging cell biology in the 21st century

Sensory-Motor Integration: More Variability Reduces Individuality

In Search of the Missing Ligands for TetR Family Regulators

Adding Specificity to Artificial Transcription Activators

Finding the Missing Code of RNA Recognition by PUF Proteins

Paul B. Whittredge, Justin W. Taraska Chemistry & Biology

Infant cognition Current Biology

Activity-Based Profiling of 2-Oxoglutarate Oxygenases

Hydra Kristine M. Glauber, Catherine E. Dana, Robert E. Steele

Targeting the Undruggable Proteome: The Small Molecules of My Dreams

No Need To Be Pure: Mix the Cultures!

Activity-Based Profiling for Drug Discovery

Confessions of a journal junkie

Volume 16, Issue 11, Pages (November 2009)

GFP Family: Structural Insights into Spectral Tuning

Now Playing: Farnesol in the Biofilm

Ribosome Evolution for Two Artificial Amino Acids in E. coli

BCR-ABL1 Kinase: Hunting an Elusive Target with New Weapons

Making a New Turn In Matrix Metalloprotease Inhibition

Volume 21, Issue 8, Pages v-vi (August 2014)

Foundations for Directed Alkaloid Biosynthesis

Discrimination between Two Endocannabinoids

Volume 18, Issue 10, Pages (October 2011)

Bivalent Aptamers Deliver the Punch

Fucci: Street Lights on the Road to Mitosis

Redesigning the Architecture of the Base Pair: Toward Biochemical and Biological Function of New Genetic Sets Andrew T. Krueger, Eric T. Kool Chemistry.

Screening for a Diamond in the Rough

Nature’s Strategy for Catalyzing Diels-Alder Reaction

L-DOPA Ropes in tRNAPhe

Volume 21, Issue 9, Pages (September 2014)

Urea Transporter Inhibitors: En Route to New Diuretics

Volume 17, Issue 7, Pages (July 2010)

Tools to Tackle Protein Acetylation

Volume 21, Issue 9, Pages (September 2014)

A New Fluorescence-Based Assay for Autophagy

Volume 18, Issue 5, Pages R198-R202 (March 2008)

Volume 22, Issue 4, Pages vii-viii (April 2015)

Presentation transcript:

Green-Red Flashers to Accelerate Biology Konstantin A. Lukyanov Chemistry & Biology Volume 18, Issue 10, Pages 1202-1204 (October 2011) DOI: 10.1016/j.chembiol.2011.10.003 Copyright © 2011 Elsevier Ltd Terms and Conditions

Figure 1 An Outline of Photoconversions of IrisFP-Like Fluorescent Proteins Fluorescent protein β-barrels are colored correspondingly to fluorescence of different states, switching between which can be achieved by illumination with light of specific wavelength and intensity (arrows). These four-state photoswitchable proteins resemble an emergency flasher with blinking green and red beacons. Chemistry & Biology 2011 18, 1202-1204DOI: (10.1016/j.chembiol.2011.10.003) Copyright © 2011 Elsevier Ltd Terms and Conditions