Maritta S. Jaakkola, MD, PhD, Reginald Quansah, PhD, Timo T

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Presentation transcript:

Association of indoor dampness and molds with rhinitis risk: A systematic review and meta-analysis Maritta S. Jaakkola, MD, PhD, Reginald Quansah, PhD, Timo T. Hugg, PhD, Sirpa A.M. Heikkinen, BSc, Jouni J.K. Jaakkola, MD, PhD Journal of Allergy and Clinical Immunology Volume 132, Issue 5, Pages 1099-1110.e18 (November 2013) DOI: 10.1016/j.jaci.2013.07.028 Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Flow diagram showing searches and study selection. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Forest plot for the relation between any exposure and rhinitis (A), between water damage and rhinitis (B), between dampness and rhinitis (C), between visible mold and rhinitis (D), and between mold odor and rhinitis (E). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Forest plot for the relation between any exposure and rhinitis (A), between water damage and rhinitis (B), between dampness and rhinitis (C), between visible mold and rhinitis (D), and between mold odor and rhinitis (E). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Forest plot for the relation between any exposure and rhinitis (A), between water damage and rhinitis (B), between dampness and rhinitis (C), between visible mold and rhinitis (D), and between mold odor and rhinitis (E). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Forest plot for the relation between any exposure and AR (A), between water damage and AR (B), between dampness and AR (C), between visible mold and AR (D), and between mold odor and AR (E). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Forest plot for the relation between any exposure and AR (A), between water damage and AR (B), between dampness and AR (C), between visible mold and AR (D), and between mold odor and AR (E). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Forest plot for the relation between any exposure and AR (A), between water damage and AR (B), between dampness and AR (C), between visible mold and AR (D), and between mold odor and AR (E). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Forest plot for the relation between any exposure and rhinoconjunctivitis (A), between dampness and rhinoconjunctivitis (B), and between visible mold and rhinoconjunctivitis (C). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Forest plot for the relation between any exposure and rhinoconjunctivitis (A), between dampness and rhinoconjunctivitis (B), and between visible mold and rhinoconjunctivitis (C). D+L, Random-effects summary EE from the DerSimonian-Laird method; I-V, fixed-effects model summary EE from the generic inverse variable method. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Funnel plot with pseudo–95% confidence limits for any exposure and rhinitis. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Funnel plot with pseudo–95% confidence limits for dampness and rhinitis. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Funnel plot with pseudo–95% confidence limits for visible mold and rhinitis. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E4 Funnel plot with pseudo–95% confidence limits for any exposure and AR. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E5 Funnel plot with pseudo–95% confidence limits for dampness and AR. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E6 Funnel plot with pseudo–95% confidence limits for any exposure and rhinoconjunctivitis. Journal of Allergy and Clinical Immunology 2013 132, 1099-1110.e18DOI: (10.1016/j.jaci.2013.07.028) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions