Increased frequencies of glutathione S-transferase(GSTM1 and GSTT1) gene deletions in Korean patients with acquired aplastic anemia by Kyung A. Lee, Sun.

Slides:

Advertisements

Similar presentations

Generating AML-Specific Peripheral Blood Autologous Cytotoxic T-Lymphocytes (CTLs)‏ by Rohtesh S. Mehta, Xiaohua Chen, Antony Jeyaraj, and Paul Szabolcs.

Advertisements

Investigating a New Methodology for the Detection of Low Frequency 17p Deleted Clones in Chronic Lymphocytic Leukaemia (CLL): Impact on Prognostic Outcome.

Functional role of alternatively spliced deoxycytidine kinase in sensitivity to cytarabine of acute myeloid leukemic cells by Marjan J. T. Veuger, Mirjam.

NPM1, IDH1/2 and DNAH11 Gene Mutations Can Improve a Prognostic Stratification of Acute Myeloid Leukemia Patients with Normal Karyotype but Not Harboring.

Impact Of CMV Reactivation On Relapse In Patients With Acute Leukemia Who Received Allogeneic Stem Cell Transplantation In First Remission: Possible GVL.

The effect of antiviral therapy on t(14;18) translocation and immunoglobulin gene rearrangement in patients with chronic hepatitis C virus infection by.

Influence of GST Gene Polymorphisms on the Clearance of Intravenous Busulfan in Adult Patients Undergoing Hematopoietic Cell Transplantation Sung-Doo.

Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene by A.

Higher Frequency of Glutathione S-Transferase Deletions in Black Children With Acute Lymphoblastic Leukemia by Chun-Lin Chen, Qing Liu, Ching-Hon Pui,

Deletions within the HSV-tk transgene in long-lasting circulating gene-modified T cells infused with a hematopoietic graft by Marina Deschamps, Patricia.

Improved Outcome of a Reduced Toxicity-Fludarabine, Cyclophosphamide, plus Antithymocyte Globulin Conditioning Regimen for Unrelated Donor Transplantation.

by Jurgen Seppen, Simon C. Barry, Brandon Harder, and William R. A

In Vivo Tropism of Hepatitis C Virus Genomic Sequences in Hematopoietic Cells: Influence of Viral Load, Viral Genotype, and Cell Phenotype by Hervé Lerat,

A Rapid Polymerase Chain Reaction-Based Screening Method for Identification of All Expanded Alleles of the Fragile X (FMR1) Gene in Newborn and High-Risk.

Erythroblastic Inclusions in Dominantly Inherited β Thalassemias

P16 INK4a andp15 INK4b gene methylations in plasma cells from monoclonal gammopathy of undetermined significance by Gaëlle Guillerm, Emmanuel Gyan, Darius.

Unrelated Donor Bone Marrow Transplants for Severe Aplastic Anemia with Conditioning Using Total Body Irradiation and Cyclophosphamide Sung-Yong Kim,

Passage-Dependent Cancerous Transformation Of Human Mesenchymal Stem Cell Of Adipose Origin During In Vitro Culture by Jung Ah Kim, Qute Choi, Kyong Ok.

by Martin de Boer, Egbert Bakker, Stefaan Van Lierde, and Dirk Roos

Diagnostic Application of an Extensive Gene Panel for Leber Congenital Amaurosis with Severe Genetic Heterogeneity Moon-Woo Seong, Soo Hyun Seo, Young.

Homozygous deletion of HFE: the Sardinian hemochromatosis?

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with.

Nested Polymerase Chain Reaction With Sequence-Specific Primers Typing for HLA-A, -B, and -C Alleles: Detection of Microchimerism in DR-Matched Individuals.

Comparison of the efficacy of rabbit and horse antithymocyte globulin for the treatment of severe aplastic anemia in children by Ayami Yoshimi, Charlotte.

The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in Africans with the Rh D-negative blood group phenotype.

Jonathan A. Schumacher, Stephen D. Jenson, Kojo S. J

Volume 69, Issue 1, Pages (January 2006)

Betaine, Dimethyl Sulfoxide, and 7-Deaza-dGTP, a Powerful Mixture for Amplification of GC-Rich DNA Sequences Marco Musso, Renata Bocciardi, Sara Parodi,

Pooja Chitgopeker, Debjani Sahni Journal of Investigative Dermatology

Yanggu Shi, Sharon F. Terry, Patrick F. Terry, Lionel G

by Alexander Röth, Andreas Hüttmann, Russell P

Rapid Simultaneous Screening of Factor V Leiden and G20210A Prothrombin Variant by Multiplex Polymerase Chain Reaction on Whole Blood by Encarnación Gómez,

Simultaneous Genotyping of GSTT1 and GSTM1 Null Polymorphisms by Melting Curve Analysis in Presence of SYBR Green I Fátima Marín, Nadia García, Xavier.

Pitfalls of Multiple Ligation-Dependent Probe Amplifications in Detecting DMD Exon Deletions or Duplications Man Jin Kim, Sung Im Cho, Jong-Hee Chae,

Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia:

Pure ground glass nodular adenocarcinomas: Are preoperative positron emission tomography/computed tomography and brain magnetic resonance imaging useful.

Prevalence of diarrheagenic Escherichia coli strains detected by PCR in patients with travelers' diarrhea M. Vargas, J. Gascón, F. Gallardo, M. T. Jimenez.

A Novel Mutation of Arg306 of Factor V Gene in Hong Kong Chinese

Association between genetic variations of vascular endothelial growth factor receptor 2 and atopy in the Korean population Heung-Woo Park, MD, Jong-Eun.

Pre-Engraftment Syndrome after Unrelated Cord Blood Transplantation: A Predictor of Engraftment and Acute Graft-versus-Host Disease Meerim Park, Soo.

Highly homologous T-cell receptor beta sequences support a common target for autoreactive T cells in most patients with paroxysmal nocturnal hemoglobinuria.

The Rhesus Macaque as an Animal Model for Hemophilia B Gene Therapy

ATM gene inactivation in mantle cell lymphoma mainly occurs by truncating mutations and missense mutations involving the phosphatidylinositol-3 kinase.

Lineage-Restricted Expression of Protein Kinase C Isoforms in Hematopoiesis by Alessandra Bassini, Giorgio Zauli, Giovanni Migliaccio, Anna Rita Migliaccio,

A new mutation in the HNF4 binding region of the factor VII promoter in a patient with severe factor VII deficiency by Josephine A. Carew, Eleanor S. Pollak,

Sex chromosome characteristics and recurrent miscarriage

Implications of Using the ND1 Gene as a Control Region for Real-Time PCR Analysis of Mitochondrial DNA Deletions in Human Skin Andrew Harbottle, Kim.

Figure 3 Transcripts of the splicing mutation (c

Volume 115, Issue 5, Pages (November 1998)

Julie Di Cristofaro, Monique Silvy, Jacques Chiaroni, Pascal Bailly

Volume 119, Issue 4, Pages (October 2000)

Use of short-term culture for identification of Mycobacterium avium subsp. paratuberculosis in tissue from Crohn's disease patients D. Schwartz, I. Shafran,

Multiplex PCR Detection of GSTM1, GSTT1, and GSTP1 Gene Variants

Somatic Mutations of Fas (Apo-1/CD95) Gene in Cutaneous Squamous Cell Carcinoma Arising from a Burn Scar Sug Hyung Lee, Min Sun Shin, Hong Sug Kim, Won.

Prevalence of inherited blood disorders and associations with malaria and anemia in Malawian children by Patrick T. McGann, Anne M. Williams, Graham Ellis,

Accurate, simple, and inexpensive assays to diagnose F8 gene inversion mutations in hemophilia A patients and carriers by Debargh Dutta, Devi Gunasekera,

Wook Lew Journal of Investigative Dermatology

Figure 1. Genomic organization of the murine Pcln1 gene.

PCR amplification of the ORF encoding the cytosolic p36 protein of M

The functional genotype of glutathione S-transferase T1 gene is strongly associated with increased risk of idiopathic infertility in Russian men Alexey.

Successful Engraftment with Fludarabine, Cyclophosphamide, and Thymoglobulin Conditioning Regimen in Unrelated Transplantation for Severe Aplastic Anemia:

Identification of differential gene expression in germinal vesicle vs

Method of Mutation Analysis May Contribute to Discrepancies in Reports of V599EBRAF Mutation Frequencies in Melanocytic Neoplasms Christopher J. Miller,

Association of a polymorphism in the ornithine decarboxylase gene with male androgenetic alopecia Rachel A. Garton, MD, Amy J. McMichael, MD, Joel Sugarman,

Polymorphic X-Chromosome Inactivation of the Human TIMP1 Gene

Diagnostic and Prognostic Implications of Prohibitin Overexpression in Normal Karyotype Acute Myeloid Leukemia by Hye-Ran Kim, Jun Hyung Lee, Min-Gu Kang,

The I1307K APC gene variant was identified using primers designed to detect the I1307K. The I1307K APC gene variant was identified using primers designed.

Representative photograph of somatic mutations detected by PCR-SSCP.

Methylation-specific PCR of APC, RASSF1A, and p14ARF genes in bladder tumor and urine DNAs. In the APC gel panel viewed from left to right, the first (TCC34)

Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Expression.

Presentation transcript:

Increased frequencies of glutathione S-transferase(GSTM1 and GSTT1) gene deletions in Korean patients with acquired aplastic anemia by Kyung A. Lee, Sun Hee Kim, Hee Yeon Woo, Young Joon Hong, and Hyoun Chan Cho Blood Volume 98(12):3483-3485 December 1, 2001 ©2001 by American Society of Hematology

Multiplex PCR products analyzed on 2% agarose gel Multiplex PCR products analyzed on 2% agarose gel.The presence or absence of GSTM1 and GSTT1 genes was detected by the presence or absence of a band at 480 base pair (bp) (corresponding to GSTT1) and a band at 215 bp (corresponding to GSTM1). Multiplex PCR products analyzed on 2% agarose gel.The presence or absence of GSTM1 and GSTT1 genes was detected by the presence or absence of a band at 480 base pair (bp) (corresponding to GSTT1) and a band at 215 bp (corresponding to GSTM1). A band at 312 bp (corresponding to 1A1gene) was always present and was used as an internal control to document successful PCR amplification. Lanes 1,5, individuals withGSTT1 +/+ andGSTM1 +/+; lanes 2,7, individuals with GSTT1 −/− andGSTM1 +/+ alleles; lane 4, individuals with GSTT1 +/+ andGSTM1 −/− alleles; lanes 3,6,8, individuals with deletions for both GSTM1 andGSTT1. Kyung A. Lee et al. Blood 2001;98:3483-3485 ©2001 by American Society of Hematology