Repeal and Replace: Adipocyte Regeneration in Wound Repair

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Presentation transcript:

Repeal and Replace: Adipocyte Regeneration in Wound Repair Valerie Horsley, Fiona Watt Cell Stem Cell Volume 20, Issue 4, Pages 424-426 (April 2017) DOI: 10.1016/j.stem.2017.03.015 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Model of the Mesenchymal Cell Heterogeneity and Lineages in the Skin CD24+, Sca1+ adipocyte stem cells and Sca1+ adipocyte precursor cells generate mature adipocytes in non-wounded skin. Fibroblast lineages that express CD26 and Engrailed1 can generate myofibroblasts in skin wounds. Plikus et al. reveal that myofibroblasts generate mature adipocytes in large skin wounds. Whether a myofibroblast progenitor or adipocyte stem or precursor cell can generate myofibroblasts is not known. Cell Stem Cell 2017 20, 424-426DOI: (10.1016/j.stem.2017.03.015) Copyright © 2017 Elsevier Inc. Terms and Conditions