Phase-sensitive X-ray imaging of synovial joints

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Presentation transcript:

Phase-sensitive X-ray imaging of synovial joints J. Li, Z. Zhong, D. Connor, J. Mollenhauer, C. Muehleman Osteoarthritis and Cartilage Volume 17, Issue 9, Pages 1193-1196 (September 2009) DOI: 10.1016/j.joca.2009.03.005 Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Schematic diagram of the analyzer-based imaging setup showing the double-crystal monochromator and analyzer crystal, the essential elements of the technology. Osteoarthritis and Cartilage 2009 17, 1193-1196DOI: (10.1016/j.joca.2009.03.005) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Frontal slice image of a cadaveric human knee joint showing soft tissues and bone. Articular hyaline cartilage and fibrocartilage of the menisci are visible. Contrast heterogeneities within the articular cartilage are representative of cartilage degeneration as has been shown in our previous planar work. These contrast heterogeneities occur where the normally smooth articular cartilage edge is disrupted within an area, thus creating numerous edges with new refractive borders. Osteoarthritis and Cartilage 2009 17, 1193-1196DOI: (10.1016/j.joca.2009.03.005) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Sagittal slice image of a cadaveric human knee joint. Salient features are labeled. Note that even the collagen fiber bundles of the anterior cruciate ligament (ACL) are identifiable. Boundaries between the cartilages of the patella and of the trochlear surface of the femur are not easily distinguishable in this image due to the angle of these boundaries with respect to the beam; edge enhancement may be lessened when exactly perpendicular to the beam. This can be alleviated by more optimal positioning of the joint prior to imaging. Note the high quality of the bone features simultaneous with soft tissue features, something not possible with MRI. Osteoarthritis and Cartilage 2009 17, 1193-1196DOI: (10.1016/j.joca.2009.03.005) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Sagittal slice image of a cadaveric human knee with salient features labeled. The border of the cartilage of the femoral trochlear surface is identified at the open arrows. Collagen fiber bundles of the patellar tendon are visible. Note the clarity of the cortical and trabecular bone simultaneous with soft tissue features. Osteoarthritis and Cartilage 2009 17, 1193-1196DOI: (10.1016/j.joca.2009.03.005) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions