Dendrite Plasticity: Branching Out for Greener Pastures

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Dendrite Plasticity: Branching Out for Greener Pastures Matthew P. Klassen, Quan Yuan  Current Biology  Volume 23, Issue 16, Pages R687-R688 (August 2013) DOI: 10.1016/j.cub.2013.07.036 Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 1 Schematic diagram of the IL2QDL and IL2QVL neurons in the C. elegans head. Non-dauer IL2 neurons extend a single unbranched sensory dendrite (blue) anteriorly into the inner labial sensillium, with a simple axon (red) extending posteriorly from the soma into the nerve ring. When conditions favor dauer formation, IL2 neurons rapidly remodel their neurites, with the dendrite undergoing extensive arborization within the local body quadrant, a process that requires the furin homolog KPC-1. The axon (red) is remodeled in an indeterminate fashion which awaits future study. When conditions favor the exit from dauer and a return to normal development, this complex branching pattern is largely pruned, returning the neuron to its basal morphology. Current Biology 2013 23, R687-R688DOI: (10.1016/j.cub.2013.07.036) Copyright © 2013 Elsevier Ltd Terms and Conditions