Cardiovascular Disease Resulting From a Diet and Lifestyle at Odds With Our Paleolithic Genome: How to Become a 21st-Century Hunter-Gatherer James H.

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Presentation transcript:

Cardiovascular Disease Resulting From a Diet and Lifestyle at Odds With Our Paleolithic Genome: How to Become a 21st-Century Hunter-Gatherer James H. O'Keefe, MD, Loren Cordain, PhD Mayo Clinic Proceedings Volume 79, Issue 1, Pages 101-108 (January 2004) DOI: 10.4065/79.1.101 Copyright © 2004 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 1 The Indo-Mediterranean Diet Heart Study32 showed a reduction of cardiac deaths and myocardial infarctions in patients on the intervention diet (a traditional Mediterranean diet high in omega-3 fats, fruits, and vegetables and low in saturated fat) compared with a standard American Heart Association (control) diet. Mayo Clinic Proceedings 2004 79, 101-108DOI: (10.4065/79.1.101) Copyright © 2004 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 2 The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico Prevenzione study33 showed a 45% reduction in sudden cardiac death (SCD) among patients receiving a concentrated fish oil supplement containing approximately 850 mg of omega-3 fats. Mayo Clinic Proceedings 2004 79, 101-108DOI: (10.4065/79.1.101) Copyright © 2004 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 3 Average per capita consumption of sugar in England (1815-1970) and in the United States (1970-2000).44 Mayo Clinic Proceedings 2004 79, 101-108DOI: (10.4065/79.1.101) Copyright © 2004 Mayo Foundation for Medical Education and Research Terms and Conditions