Pigmentation in Rev3l-deleted interfollicular epidermis with wounding, UV radiation, or TPA application. Pigmentation in Rev3l-deleted interfollicular.

Slides:

Advertisements

Similar presentations

Characterization of ET1ep-/- mouse line

Advertisements

Melanoma By Liam Hanrahan. What is Melanoma? Melanoma is the fourth most common cancer, usually appearing as a pigmented skin lesion. Australia has the.

Altered cell migration factors and increased intestinal tumorigenesis in APC1638N/+ mice. Altered cell migration factors and increased intestinal tumorigenesis.

Long-term decrease of IEC migration after 56Fe radiation relative to γ-rays. Long-term decrease of IEC migration after 56Fe radiation relative to γ-rays.

PV-PV mice exposed to 1-Hz pulses show greater distance traveled and mean speed in the arena following the 4-wk protocol (Post). PV-PV mice exposed to.

Heavy-ion radiation decreases expression of key cellular tight junction proteins and alters microtubule dynamics in mouse intestine. Heavy-ion radiation.

Poly-GR and poly-PR co-aggregate with ribosomal proteins in C9orf72 patients. Poly-GR and poly-PR co-aggregate with ribosomal proteins in C9orf72 patients.

Hee-Young Park, PhD, Jin Lee, Sameer Kapasi, Shaun Peterson, Barbara A

Ocular defects produced by Daam1 mutation and in combination with diabetes. Ocular defects produced by Daam1 mutation and in combination with diabetes.

Aberrant wound architecture and proliferation in Rev3l-deficient skin.

Figure 3. Effect of HPD on basal cell proliferation in mouse skin

Volume 19, Issue 11, Pages (June 2017)

INT-767 treatment prevents renal lipid accumulation in diabetic DBA/2J mice. INT-767 treatment prevents renal lipid accumulation in diabetic DBA/2J mice.

Vitali Alexeev, Kyonggeun Yoon Journal of Investigative Dermatology

Prmt7 deficiency causes a fiber-type switch toward glycolytic.

Approach for the Derivation of Melanocytes from Induced Pluripotent Stem Cells Tamihiro Kawakami, Tatsuro Okano, Sora Takeuchi, Kayoko Osumi, Yoshinao.

Renal microvascular injury 6 months after induction of JG cell-specific Gsα knockout. Renal microvascular injury 6 months after induction of JG cell-specific.

Dedicated Epithelial Recipient Cells Determine Pigmentation Patterns

LATS2 is a tumor suppressor in a mouse lumB breast cancer model.

In Vivo Role of Vitamin D Receptor Signaling in UVB-Induced DNA Damage and Melanocyte Homeostasis Sharmeen Chagani, Sergiy Kyryachenko, Yoko Yamamoto,

CCL21 localizes to T cell zone FRCs in young and aged spleens.

Melanocytes in Rev3l-deficient epidermis following UV radiation, wounding, or TPA. Melanocytes in Rev3l-deficient epidermis following UV radiation, wounding,

Suppression of Progressive Loss of Coat Color in Microphthalmia-Vitiligo Mutant Mice Kei Kurita, Maki Nishito, Hisao Shimogaki, Koji Takada, Hidetoshi.

Fibroblast proliferation and ECM changes during wound healing

The pathophysiological processes linked to kidney disease.

The pho4Δ mutant is less virulent than the WT strain in intranasal (A to C) and intravenous (D to F) models of cryptococcosis. The pho4Δ mutant is less.

Peptidergic nociceptor markers are reduced in DRG from Nav-Tsc2 mice.

NrasG12D induces CNS tumors in mice.

Protection against UVR Involves MC1R-Mediated Non-Pigmentary and Pigmentary Mechanisms In Vivo Samantha Robinson, Sandra Dixon, Suzannah August, Brian.

Development of a New Mouse Model (Xeroderma Pigmentosum A-Deficient, Stem Cell Factor-Transgenic) of Ultraviolet B-Induced Melanoma Fumikazu Yamazaki,

Reduction of RPA2 foci in Rec114−/− meiocytes

BDNF expression in the cerebellum and brain stem region.

Masahiro Hara, Mina Yaar, H

Inhibition of Melanosome Transfer Results in Skin Lightening1

Regulation of Human Skin Pigmentation in situ by Repetitive UV Exposure: Molecular Characterization of Responses to UVA and/or UVB Wonseon Choi, Yoshinori.

Defect of cerebellar development and malformation of Purkinje cells in Pex14ΔC/ΔC BL/ICR mice. Defect of cerebellar development and malformation of Purkinje.

ILK knockdown decreases mTOR signaling in PKD kidneys.

Sebastiano Sciarretta et al. JACC 2018;71:

Distribution of splenic T cells, B cells, and NK cells in NSG hL-7xhIL-15 humanized mice. Distribution of splenic T cells, B cells, and NK cells in NSG.

Endogenous SMN1 is not recruited to stress granules in HeLa cells after diverse stresses. Endogenous SMN1 is not recruited to stress granules in HeLa cells.

Pericytes promote epidermal regeneration in OCs that most closely resembles human skin epidermis. Pericytes promote epidermal regeneration in OCs that.

The effects of KY19382 on growth plate senescence and longitudinal bone growth. The effects of KY19382 on growth plate senescence and longitudinal bone.

TSA causes premature chromatid sister separation.

Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.

Challenge with oxazolone results in epithelial hyperplasia and influx of inflammatory cells into the epidermis and dermis and keratosis as observed in.

Sox2 and Isl1 cooperate to orchestrate Merkel cell differentiation.

DDR1 plays an intrinsic role in primary epithelial cells undergoing branching morphogenesis and is required for correct organization of the basement membrane.

Histology of 15-day wounds reveals marked differences in the outcome of the repair process. Histology of 15-day wounds reveals marked differences in the.

Fig. 3. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice.

Single 2-μm histological section from 140 serial sections used to quantify relative abundance of intravasating large protrusions, intravasating proplatelets,

Higher levels of PEDF-impaired skin structure and function.

Chop deletion preserves β-cell function in P58IPK−/− mice.

Fig. 4. Deletion of Baf60c in myocardium results in dilated chambers and impaired cardiac function. Deletion of Baf60c in myocardium results in dilated.

Human diversity.

PEDF inhibits Wnt/T-cell factor/β-catenin signaling in resting and wounded skin. PEDF inhibits Wnt/T-cell factor/β-catenin signaling in resting and wounded.

Glucose-stimulated insulin secretion, plasma glucagon levels, and pancreatic hormone contents. Glucose-stimulated insulin secretion, plasma glucagon levels,

Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. Lack of Ctip2.

Gene deletion of PGC-1α leads to the loss of dopamine neurons in the SNpc. Gene deletion of PGC-1α leads to the loss of dopamine neurons in the SNpc. A,

A: Representative sections from the LV of sham and diabetic Ntg and IGF-1R mice. A: Representative sections from the LV of sham and diabetic Ntg and IGF-1R.

Upon challenge with oxazolone, human leukocytes (mainly consisting of T cells) infiltrate the dermis and epidermis. Upon challenge with oxazolone, human.

IKKβ protects adipocytes from HFD-induced cell death.

Activin overexpression leads to keratinocytic cysts and high cell density in the granulation tissue of healed wounds. Activin overexpression leads to keratinocytic.

Histopathologic characteristics in HL-mice and HL-HPS-mice.

Suppression by nobiletin of TPA-induced skin morphological changes observed by H&E staining. Suppression by nobiletin of TPA-induced skin morphological.

Suppression by nobiletin of the TPA-induced increase in PCNA-positive cells in mouse epidermis. Suppression by nobiletin of the TPA-induced increase in.

Characterization of a Composite Tissue Model that Supports Clonal Growth of Human Melanocytes In Vitro and In Vivo Daniel A. Medalie, Ronald G. Tompkins,

Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8 and Stat3+/+:HPV8 mice. Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8.

Chronic Treg reduction exacerbates bleomycin-induced skin fibrosis.

Axin induces extensive apoptosis in the lymphocytes of DDTg mice.

Fig. 5 Distributions of cell nuclear area values and internuclear distances in the breast tumor specimens (Figs. 3 and 4), where bin interval = 8 and n.

Presentation transcript:

Pigmentation in Rev3l-deleted interfollicular epidermis with wounding, UV radiation, or TPA application. Pigmentation in Rev3l-deleted interfollicular epidermis with wounding, UV radiation, or TPA application. Fontana-Masson staining of skin sections from BK5.Cre; Rev3l+/lox and BK5.Cre; Rev3l−/lox mice (A) 3 d after wounding, (B) 10 d after UV radiation, or (C) 2 wk after TPA application. Melanin pigment stains black. Distance bar: 100 μm. Sabine S Lange et al. LSA 2018;1:e201800048 © 2018 Lange et al.