Brandon J. Sumpio, BA, Gianluca Citoni, MD, Jason A. Chin, MD, Bauer E

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Use of hyperspectral imaging to assess endothelial dysfunction in peripheral arterial disease Brandon J. Sumpio, BA, Gianluca Citoni, MD, Jason A. Chin, MD, Bauer E. Sumpio, MD, PhD Journal of Vascular Surgery Volume 64, Issue 4, Pages 1066-1073 (October 2016) DOI: 10.1016/j.jvs.2016.03.463 Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 1 A, Absolute and (B) percentage changes in oxygenated (oxy) hemoglobin (oxyHb) and deoxygenated (deoxy) hemoglobin (deoxyHb) changes after suprasystolic brachial artery cuff occlusion for 5 minutes in participants without peripheral artery disease (PAD) or coronary artery disease (CAD) measured in the upper arm (upper), forearm (fore), and hand. Comparison was made between all participants (black columns), those aged >40 years (hatched light gray columns), and those aged <40 years (dark gray columns). The error bars show the standard deviation. *P < .05 comparing participants aged >40 years vs those aged <40 years. Journal of Vascular Surgery 2016 64, 1066-1073DOI: (10.1016/j.jvs.2016.03.463) Copyright © 2016 Society for Vascular Surgery Terms and Conditions

Fig 2 Oxygenated hemoglobin (oxyHb) and deoxygenated hemoglobin (deoxyHb) changes after suprasystolic brachial artery cuff occlusion for 5 minutes measured in the upper arm, forearm, and hand in participants without peripheral artery disease (PAD) or coronary artery disease (CAD) and those with PAD only or PAD and CAD. Comparison was made between participants aged >40 years (black columns) and those with PAD or CAD (diagonal columns) or PAD only (gray speckled columns). A, Absolute and (B) percentage change in oxyHb. C, Absolute and (D) percentage change in deoxyHb. The error bars show the standard deviation. *P < .05 vs participants without PAD or CAD. Journal of Vascular Surgery 2016 64, 1066-1073DOI: (10.1016/j.jvs.2016.03.463) Copyright © 2016 Society for Vascular Surgery Terms and Conditions