Maternal Vitamin D Supplementation to Improve the Vitamin D Status of Breast-fed Infants: A Randomized Controlled Trial Sara S. Oberhelman, MD, Michael.

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Presentation transcript:

Maternal Vitamin D Supplementation to Improve the Vitamin D Status of Breast-fed Infants: A Randomized Controlled Trial Sara S. Oberhelman, MD, Michael E. Meekins, PharmD, Philip R. Fischer, MD, Bernard R. Lee, PharmD, Ravinder J. Singh, PhD, Stephen S. Cha, MS, Brian M. Gardner, PharmD, John M. Pettifor, MB, BCh, PhD, Ivana T. Croghan, PhD, Tom D. Thacher, MD Mayo Clinic Proceedings Volume 88, Issue 12, Pages 1378-1387 (December 2013) DOI: 10.1016/j.mayocp.2013.09.012 Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 1 Maternal vitamin D metabolite values with 2 vitamin D supplementation regimens: serum 25-hydroxyvitamin D (25[OH]D) (A), serum cholecalciferol (B), and breast milk cholecalciferol (C). Error bars represent SD. Mayo Clinic Proceedings 2013 88, 1378-1387DOI: (10.1016/j.mayocp.2013.09.012) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions

Figure 2 25-Hydroxyvitamin D (25[OH]D) concentrations in breast-fed infants in response to 2 vitamin D supplementation regimens of their mothers. Error bars represent SD. The upper error bars are the SD for the 5000 IU/d group, and the lower error bars are the SD for the 150,000 IU single-dose group. Mayo Clinic Proceedings 2013 88, 1378-1387DOI: (10.1016/j.mayocp.2013.09.012) Copyright © 2013 Mayo Foundation for Medical Education and Research Terms and Conditions