A b c d Figure 1: Strong T2 weighted images (inversion recovery sequences with fat suppression, TIRM) of a 18 year-old girl document a significant reduction.

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a b c d Figure 1: Strong T2 weighted images (inversion recovery sequences with fat suppression, TIRM) of a 18 year-old girl document a significant reduction in magnetic resonance imaging (MRI) signal intensity after 3 monthly pamidronate infusions (a, b) acompanied by a significant reduction in pain. However after further 6 treatments, reoccurence of pain was noted in the sternum and the spine while the patient was still treated. Another MRI revealed new sternal (c) lesions and a new spinal lesion (arrow) (d).