Transport of Oxygen 3% in dissolved form i. e. dissolved in plasma. 97% bound to Haemoglobin

O2 Transport as dissolved in plasma At Arterial Po2 = 0.29 ml of O2 dissolved in 100 ml of blood At Venous Po2 = 0.12 ml of O2 dissolved in 100 ml of blood 0.17 ml of O2 is carried in dissolved state to tissue by each 100 ml of blood

O2 transport as bound to Hb 1gm Hb can carry = 1.39 ml of O2. But due to impurities like met Hb 1gm Hb carries 1.34 ml of O2 15 gms will carry 1.34 x 15 = 20.10 ml of O2 This happens at or more than 250 mmHg when Hb is 100% saturated. At arterial PO2 only 97% of Hb is saturated

O2 transport as bound to Hb At arterial PO2 19.4 ml of O2 is bound to Hb. At venous PO2 14.4 ml of O2 is bound to Hb. 5 ml of O2 is transported as bound form from lungs to tissues by each 100 ml of blood.

O2 Hb dissociation curve

Factors affecting O2 Hb dissociation curve CO2--------- Bohr effect Hydrogen Ion Temperature BPG( Bisphosphoglycerate ) Electrolytes Met Hb HbF Hormones