Danny R. Youlden, BSc, Susanna M. Cramb, MPH, Peter D. Baade, PhD 

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The International Epidemiology of Lung Cancer: Geographical Distribution and Secular Trends  Danny R. Youlden, BSc, Susanna M. Cramb, MPH, Peter D. Baade, PhD  Journal of Thoracic Oncology  Volume 3, Issue 8, Pages 819-831 (August 2008) DOI: 10.1097/JTO.0b013e31818020eb Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 International variation in age-standardized lung cancer incidence rates (per 100,000 population) in 2002. Notes: 1. Rates age-standardized to the WHO World Standard Population.25 Source: GLOBOCAN 2002, International Agency for Research on Cancer (IARC).26 2. Lung cancer incidence rates for females are represented in the top map and for males in the bottom map. 3. The numbers in brackets shown in the legend signify how many countries are included in that incidence range. Journal of Thoracic Oncology 2008 3, 819-831DOI: (10.1097/JTO.0b013e31818020eb) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Recent trends in lung cancer incidence by sex for selected countries/registry areas, 1980–2004. Data sources: Australian Institute of Health and Welfare (Australia); Public Health Agency of Canada (Canada); Thames Cancer Registry (South-East England); National Cancer Registry of Ireland (Ireland); National Cancer Centre (Japan); National Cancer Institute (USA). Notes: 1. y axis represents ‘Incidence rate per 100,000 population per year’ and x axis represents ‘Year’. 2. Incidence rates have been age-standardized to the WHO World Standard Population.25 3. Trends modeled using Joinpoint software (version 3.0), National Cancer Institute.43 Journal of Thoracic Oncology 2008 3, 819-831DOI: (10.1097/JTO.0b013e31818020eb) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Percent of total Years of Life Lost (YLLs) due to lung cancer, by region, 2002. Data source: World Health Organization (WHO).96 Note: Western Pacific Region A includes Australia, Brunei, New Zealand, Japan and Singapore. Western Pacific Region B incorporates all other countries in this region, including China, Mongolia, Republic of Korea and the Pacific Island nations.97 Journal of Thoracic Oncology 2008 3, 819-831DOI: (10.1097/JTO.0b013e31818020eb) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Recent trends in lung cancer mortality by sex for selected countries, 1980–2005 Data source: World Health Organization (WHO).102 Notes: (1) Countries were selected on the basis of having lung cancer mortality data of sufficient quality (at least 80% of all deaths registered, except China, which was based on a sample of less than 10% of all deaths) and quantity (average of at least 300 lung cancer deaths per year for males and 250 deaths per year for females). (2) y axis represents 'Incidence rate per 100,000 population per year' and x axis represents ‘Year.’ (3) Rates age-standardized to the WHO World Standard Population.25 (4) Trends modeled using Joinpoint software (version 3.0), National Cancer Institute.43 Journal of Thoracic Oncology 2008 3, 819-831DOI: (10.1097/JTO.0b013e31818020eb) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions