Methotrexate improves biochemical tests in patients with primary biliary cirrhosis who respond incompletely to ursodiol Peter A.L. Bonis, Marshall Kaplan

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Methotrexate improves biochemical tests in patients with primary biliary cirrhosis who respond incompletely to ursodiol Peter A.L. Bonis, Marshall Kaplan Gastroenterology Volume 117, Issue 2, Pages 395-399 (August 1999) DOI: 10.1053/gast.1999.0029900395

1 Fig. 1. Changes in mean serum ALP levels after treatment with UDCA and colchicine and after addition of methotrexate (MTX) to the treatment regimen. N, number of patients for whom data were available at each time point. Vertical bars indicate the range of values at each interval. Gastroenterology 1999 117, 395-399DOI: (10.1053/gast.1999.0029900395)

2 Fig. 2. Box plot showing ALP levels at baseline, after treatment with UDCA and colchicine (Colch), and after combination therapy. MTX, methotrexate. The top and bottom of each box represent values defining the third and first quartile of the data. Heavy line indicates midpoint of the distribution; T-bars represent the range of values. Gastroenterology 1999 117, 395-399DOI: (10.1053/gast.1999.0029900395)