Freebie Rhabdomyolysis: A Public Health Concern Freebie Rhabdomyolysis: A Public Health Concern. Spin Class-Induced Rhabdomyolysis  Maureen Brogan, MD, Rudrick Ledesma, MD, Alan Coffino, MD, PhD, Praveen Chander, MD  The American Journal of Medicine  Volume 130, Issue 4, Pages 484-487 (April 2017) DOI: 10.1016/j.amjmed.2016.11.004 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 A representative hematoxylin & eosin-stained section reveals several tubules dilated with eosinophilic granulated cast focally surrounded by desquamated epithelial cells. Many of the surrounding tubules show nonspecific degenerative changes suggestive of acute tubular injury. Glomeruli and blood vessels are essentially unremarkable (original magnification ×25). The American Journal of Medicine 2017 130, 484-487DOI: (10.1016/j.amjmed.2016.11.004) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 2 A representative section stained with specific antiserato myoglobin reveals tubular casts staining positive for myoglobin suggestive of acute myoglobinuric acute renal failure (original magnification ×25). The American Journal of Medicine 2017 130, 484-487DOI: (10.1016/j.amjmed.2016.11.004) Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 3 Cytochrome C staining with histochemical technique shows significant positive staining in most tubules but with focal heterogeneity possibly secondary to injury. The American Journal of Medicine 2017 130, 484-487DOI: (10.1016/j.amjmed.2016.11.004) Copyright © 2016 Elsevier Inc. Terms and Conditions