– defensive avoidance defensive distance defensive

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+ + + + + + + – defensive avoidance defensive distance defensive approach PREFRONTAL - OCD: deep VENTRAL STREAM complex fear PREFRONTAL Complex Anxiety DORSAL STREAM (e.g. social) ANTERIOR OCD - shallow CINGULATE simple obsession POSTERIOR Obsessional anxiety: CINGULATE cognition/rumination + + AMYGDALA Phobia: avoid SEPTO-HIPPO- Cognition/aversion CAMPAL SYSTEM + + AMYGDALA Phobia: arousal AMYGDALA Arousal/startle + + MEDIAL Phobia: HYPOTHALAMUS escape MEDIAL Risk assessment HYPOTHALAMUS + PERIAQUEDUCTAL Panic: GRAY explode/freeze PERIAQUEDUCTAL Defensive quiescence GRAY – 5HT