Volume 1, Issue 2, Pages (March 2015)

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Presentation transcript:

Volume 1, Issue 2, Pages 49-50 (March 2015) An unusual cutaneous of B-cell chronic lymphocytic leukemia presenting as a massive left-sided body ecchymosis Lilia Bekel, MD, Florie Dhaille, MD, Guillaume Chaby, MD, Henri Sevestre, MD, PhD, Bruno Royer, MD, Caroline Defossez-Tribout, MD, Florian Lombart, MD, Ali Dadban, MD, Catherine Lok, MD, PhD JAAD Case Reports Volume 1, Issue 2, Pages 49-50 (March 2015) DOI: 10.1016/j.jdcr.2014.12.001 Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 A and B, Extensive left-sided ecchymosis on the left thorax (A), and left upper (A) and lower extremities (B). C, Histologic sections show perivascular infiltration of leukemia cells in the dermis. Dilated superficial dermal vessels were noted. D-F, Immunohistochemical studies found that the leukemic cells were positive for CD20 (D), CD23 (E), and CD5 (F). G, Complete resolution of the left-sided ecchymosis 8 months after a combination treatment of bendamustine and rituximab. (A and B, Hematoxylin-eosin stain; original magnifications: ×100; C and D, immunohistochemical stains; original magnifications: ×200.) JAAD Case Reports 2015 1, 49-50DOI: (10.1016/j.jdcr.2014.12.001) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions