Do NSAIDs Affect Longitudinal Changes in Knee Cartilage Volume and Knee Cartilage Defects in Older Adults? Changhai Ding, MD, Flavia Cicuttini, PhD,

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Do NSAIDs Affect Longitudinal Changes in Knee Cartilage Volume and Knee Cartilage Defects in Older Adults? Changhai Ding, MD, Flavia Cicuttini, PhD, Graeme Jones, MD The American Journal of Medicine Volume 122, Issue 9, Pages 836-842 (September 2009) DOI: 10.1016/j.amjmed.2009.03.022 Copyright © 2009 Terms and Conditions

Figure Comparison of tibial cartilage loss per annum over 2.9 years between use of selective COX-2 inhibitors and use of conventional NSAIDs. Cartilage loss was adjusted for sex, age, body mass index, knee pain, smoking, lower-limb muscle strength, baseline cartilage volume, tibial bone area, subchondral bone marrow edema, radiographic osteoarthritis, and rheumatoid arthritis. The American Journal of Medicine 2009 122, 836-842DOI: (10.1016/j.amjmed.2009.03.022) Copyright © 2009 Terms and Conditions