Gerry P. Crossan, Juan I. Garaycoechea, Ketan J. Patel Cell Stem Cell

Slides:

Advertisements

Similar presentations

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Advertisements

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI Arno F. Alpi, Paul E. Pace, M. Madan Babu, Ketan J. Patel.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Distinct Self-Renewal and Differentiation Phases in the Niche of Infrequently Dividing Hair Follicle Stem Cells Ying V. Zhang, Janice Cheong, Nichita Ciapurin,

Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart Moshi Song, Gerald W. Dorn Cell Metabolism Volume 21, Issue.

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair Francesco S. Loffredo, Matthew L. Steinhauser,

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia Tim C.P. Somervaille, Michael L. Cleary Cancer Cell.

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle Isabel Beerman, Jun Seita, Matthew A.

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Kevin G. Chen, Barbara S. Mallon, Ronald D.G. McKay, Pamela G. Robey

Chemotherapy and Cancer Stem Cells

Cutaneous Cancer Stem Cells: β-Catenin Strikes Again

Stress Can Be a Good Thing for Blood Formation

Cancer: Inappropriate Expression of Stem Cell Programs?

Kevin G. Chen, Barbara S. Mallon, Ronald D.G. McKay, Pamela G. Robey

Scott N. Freeman, Kathryn A. Burke, Menfo A. Imoisili, Timothy R. Coté

Volume 20, Issue 2, Pages (February 2017)

Volume 1, Issue 1, Pages (June 2007)

“Ring-Fencing” BRCA1 Tumor Suppressor Activity

Cell Cycle Rules Pluripotency

A Path to Insulin Independence: “The End of the Beginning”

Volume 9, Issue 2, Pages (August 2011)

Volume 16, Issue 6, Pages (June 2015)

Blocking HIF1α Activity Eliminates Hematological Cancer Stem Cells

Volume 2, Issue 6, Pages (June 2008)

Anselme Perrier, Marc Peschanski Cell Stem Cell

Public Private Partnerships: A Marriage of Necessity

MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois

MDS Is a Stem Cell Disorder After All

“Ring-Fencing” BRCA1 Tumor Suppressor Activity

Transplantable Liver Organoids Made from Only Three Ingredients

Volume 14, Issue 2, Pages (February 2014)

Regulating Cancer Stem Cells the miR Way

Stem Cell Therapies in Clinical Trials: Progress and Challenges

Time to Relax: Mechanical Stress Release Guides Stem Cell Responses

Cancer Cell of Origin: Spotlight on Luminal Progenitors

On the Origin of the Term “Stem Cell”

Cutaneous Cancer Stem Cells: β-Catenin Strikes Again

CHD7 in Charge of Neurogenesis

Volume 20, Issue 2, Pages (February 2017)

Blocking HIF1α Activity Eliminates Hematological Cancer Stem Cells

Putting Two Heads Together to Build a Better Brain

Not So Lonely at the Top for Cancer Stem Cells

Volume 18, Issue 2, Pages (February 2016)

Pluripotent Stem Cells and Disease Modeling

Transplantable Liver Organoids Made from Only Three Ingredients

Looking Back: Cancer Stem Cells

Meddling with METTLs in Normal and Leukemia Stem Cells

Regulating Autologous Adult Stem Cells: The FDA Steps Up

NO Signals from the Cancer Stem Cell Niche

Waddington’s Valleys and Captain Cook’s Islands

Volume 22, Issue 4, Pages (April 2018)

Regulating Autologous Adult Stem Cells: The FDA Steps Up

Chapter 29 - Stem Cells and Generation of New Cells in the

Chapter 77 Cervical Cancer: Burden of Disease

Looking Back: Cancer Stem Cells

Presentation transcript:

Do Mutational Dynamics in Stem Cells Explain the Origin of Common Cancers? Gerry P. Crossan, Juan I. Garaycoechea, Ketan J. Patel Cell Stem Cell Volume 16, Issue 2, Pages 111-112 (February 2015) DOI: 10.1016/j.stem.2015.01.009 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Mutations and Cancer Risk Tissues with a greater number of cumulative stem cell divisions (e.g., colon) have an increased risk of accumulating mutations (in red), eventually resulting in cancer. Cell Stem Cell 2015 16, 111-112DOI: (10.1016/j.stem.2015.01.009) Copyright © 2015 Elsevier Inc. Terms and Conditions