Decreased inhibin B responses following recombinant human chorionic gonadotropin administration in normal women and women with polycystic ovary syndrome

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Decreased inhibin B responses following recombinant human chorionic gonadotropin administration in normal women and women with polycystic ovary syndrome Rana F. Shayya, M.D., Marcus A. Rosencrantz, M.D., Sandy S. Chuan, M.D., Heidi Cook-Andersen, M.D., Ph.D., William E. Roudebush, Ph.D., H. Irene Su, M.D., M.S.E.C., Shunichi Shimasaki, Ph.D., R. Jeffrey Chang, M.D. Fertility and Sterility Volume 101, Issue 1, Pages 275-279 (January 2014) DOI: 10.1016/j.fertnstert.2013.09.037 Copyright © 2014 Terms and Conditions

Figure 1 Box and whisker plots showing median serum inhibin B (Inh B) levels and interquartile ranges at baseline and 24 hours after intravenous administration of 25 μg recombinant hCG (r-hCG) in normal and polycystic ovary syndrome (PCOS) women. The decline in Inh B following r-hCG was significant in normal (P=.002) and PCOS (P=.05) women. The closed circle above the baseline PCOS box plot denotes an Inh B value outside of the 95th percentile. Fertility and Sterility 2014 101, 275-279DOI: (10.1016/j.fertnstert.2013.09.037) Copyright © 2014 Terms and Conditions

Figure 2 Individual baseline and 24-h serum Inh B levels following intravenous administration of 25 μg r-hCG in normal and PCOS women. Abbreviations as in Figure 1. Fertility and Sterility 2014 101, 275-279DOI: (10.1016/j.fertnstert.2013.09.037) Copyright © 2014 Terms and Conditions