CHOICE study: Relative hazard of ASCVD events by baseline levels of Lp(a), LMW ApoA isoforms, and LMW ApoA isoforms with high Lp(a) vs high-molecular-weight.

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CHOICE study: Relative hazard of ASCVD events by baseline levels of Lp(a), LMW ApoA isoforms, and LMW ApoA isoforms with high Lp(a) vs high-molecular-weight ApoA and low levels of Lp(a) Measure Relative hazard p High Lp(a) concentration (>53 nmol/L vs <53 nmol/L) 1.38 0.02 LMW ApoA isoforms (<22 K-IV repeats vs >22 K-IV repeats) 1.58 <0.0005 LMW ApoA and Lp(a) level >123 nmol/L vs high-molecular-weight ApoA and Lp(a) level <123 nmol/L 1.73 Longenecker JC et al. J Am Soc Nephrol 2005; available at: http://www.jasn.org.