Joanna Wang, Chetan Bettegowda  The Journal of Molecular Diagnostics 

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Applications of DNA-Based Liquid Biopsy for Central Nervous System Neoplasms  Joanna Wang, Chetan Bettegowda  The Journal of Molecular Diagnostics  Volume 19, Issue 1, Pages 24-34 (January 2017) DOI: 10.1016/j.jmoldx.2016.08.007 Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 1 Tumors release circulating tumor DNA, circulating tumor cells, and extracellular vesicles into the bloodstream. The detection and analysis of these circulating biomarkers have utility as a liquid biopsy at multiple time points during disease management for screening, diagnosis, prognostication, and prediction. The Journal of Molecular Diagnostics 2017 19, 24-34DOI: (10.1016/j.jmoldx.2016.08.007) Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions