Why We Do What We Do, Why We Build What We Build BMS Cruiserath Biologics Project March 30th, 2016

Our New Biologics Campus at Cruiserath

823 Days to 1st GMP thaw July 1st, 2018 Our Mission Deliver the Cruiserath Large Scale Cell Culture (LSCC) project on-time, within budget, with the operational capabilities required by the Biologics Development and Operations (BDO) business unit within the bounds of safety, quality and compliance. 823 Days to 1st GMP thaw July 1st, 2018

Facility Summary Multi-product facility 400 Staff 5 to 6 campaign changeovers per year, <3 days per changeover Concurrent production in future with addition of 2nd purification suite Development Runs Q4 2017 Benchmark Schedule, Project Execution and Implementation

Immuno-Oncology

Realizing the Transformational Potential of I-O First to offer melanoma patients the possibility of long-term survival Continued strong brand performance US approvals in advanced metastatic melanoma, advanced renal cell and lung Additional global regulatory submissions

Everything We Do Is Driven By A Patient Focus