Phenomenology of neurophysiologic changes during surgical treatment of carotid stenosis using signal analysis Jonathan A. Norton, Lissa Peeling, Kotoo.

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Phenomenology of neurophysiologic changes during surgical treatment of carotid stenosis using signal analysis Jonathan A. Norton, Lissa Peeling, Kotoo Meguro, Mike Kelly Clinical Neurophysiology Practice Volume 3, Pages 28-32 (January 2018) DOI: 10.1016/j.cnp.2017.12.003 Copyright © 2018 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 1 A typical somatosensory evoked potential (SSEP) from median nerve stimulation with recordings from the contralateral somatosensory cortex. The region of the potential which was subjected to wavelet analysis is highlighted in a black solid line. The first and second derivatives were calculated on the ascending phase of the potential (baseline to N20 peak). Clinical Neurophysiology Practice 2018 3, 28-32DOI: (10.1016/j.cnp.2017.12.003) Copyright © 2018 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 2 The ‘velocity’, first derivative of the potential related to the time of clamp of the artery or the end of angioplasty (stent). Clamps were placed at −10 min and released at 0 min. The exact time of clamping varied between patients and is normalised over the time period between −10 and 0 min. Monitoring was continued for at least 30 min after the clamp was removed or 15 min after angioplasty completed. Clinical Neurophysiology Practice 2018 3, 28-32DOI: (10.1016/j.cnp.2017.12.003) Copyright © 2018 International Federation of Clinical Neurophysiology Terms and Conditions

Fig. 3 The principal coefficients of the SSEP at time zero and 15 min after clamp release, or stent deployment and in the control patients. Along the x-axis is the time from stimulation, with the onset of the up-swing occurring at 20 ms, as shown in Fig. 1. There are 6 conditions, CEA (carotid endartectomy) and stent have pre and post conditions and the unoperated and spine (control) patients have just one. Clinical Neurophysiology Practice 2018 3, 28-32DOI: (10.1016/j.cnp.2017.12.003) Copyright © 2018 International Federation of Clinical Neurophysiology Terms and Conditions