Popliteal artery aneurysms differ from abdominal aortic aneurysms in cellular topography and inflammatory markers Rob Hurks, MD, PhD, Rogier H.J. Kropman,

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Presentation transcript:

Popliteal artery aneurysms differ from abdominal aortic aneurysms in cellular topography and inflammatory markers Rob Hurks, MD, PhD, Rogier H.J. Kropman, MD, PhD, Claire W.A. Pennekamp, MD, Imo E. Hoefer, MD, PhD, Jean-Paul P.M. de Vries, MD, PhD, Gerard Pasterkamp, MD, PhD, Aryan Vink, MD, PhD, Frans L. Moll, MD, PhD Journal of Vascular Surgery Volume 60, Issue 6, Pages 1514-1519 (December 2014) DOI: 10.1016/j.jvs.2014.08.088 Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 1 Representative histology for popliteal artery aneurysm (PAA) and abdominal aortic aneurysm (AAA). Photomicrographs show a composite of hematoxylin and eosin (HE) and elastic–van Gieson (EvG) stainings. The location of the different layers is marked: I, intima; M, media; A, adventitia. Note the location of the inflammatory infiltrate, the intima in PAA and the adventitia in AAA. Furthermore, few elastin fibers remained present in both specimens, and cholesterol clefts and little amount of calcification are present in the intima of the AAA. Scale bars represent 0.5 mm. Journal of Vascular Surgery 2014 60, 1514-1519DOI: (10.1016/j.jvs.2014.08.088) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 2 Comparison of inflammatory cell presence on histology in popliteal artery aneurysm (PAA) and abdominal aortic aneurysm (AAA). Per representative field: white represents <50 cells, light gray represents 50 to 100 cells, dark gray represents 100 to 150 cells, and black represents >150 cells. Refer to the Supplementary Table for individual proportions. ***P < .001. Journal of Vascular Surgery 2014 60, 1514-1519DOI: (10.1016/j.jvs.2014.08.088) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

Fig 3 Representative Perls staining for popliteal artery aneurysm (PAA) and abdominal aortic aneurysm (AAA). Blue staining reveals the presence of iron. Scale bar indicates 0.1 mm. Journal of Vascular Surgery 2014 60, 1514-1519DOI: (10.1016/j.jvs.2014.08.088) Copyright © 2014 Society for Vascular Surgery Terms and Conditions