Correction The Journal of Allergy and Clinical Immunology: In Practice

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Correction The Journal of Allergy and Clinical Immunology: In Practice The Journal of Allergy and Clinical Immunology: In Practice Volume 6, Issue 5, Pages 1810-1812 (September 2018) DOI: 10.1016/j.jaip.2018.07.006 Copyright © 2018 Terms and Conditions

Figure 1 Algorithm for classification of urticaria and angioedema. AAE, Acquired angioedema; ACEI, angiotensin converting enzyme inhibitor; ANGPT-1, angiopoietin-1; C1-INH, C1-esterase inhibitor; CAPS, cryopyrin-associated periodic syndromes; HAE, hereditary angioedema; PAI-2, plasminogen activator inhibitor-2. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, 1810-1812DOI: (10.1016/j.jaip.2018.07.006) Copyright © 2018 Terms and Conditions

Figure 2 Mechanisms for mast cell activation in histaminergic urticaria and angioedema. FPR, N-formal peptide receptor; MRGPRX2, Mas-related G-protein coupled receptor; TLR, Toll-like receptor. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, 1810-1812DOI: (10.1016/j.jaip.2018.07.006) Copyright © 2018 Terms and Conditions

Figure 3 Mechanisms for nonhistaminergic angioedema. // indicates sites at which C1INH regulates the fibrinolytic and complement cascades, and the rationale for C1INH replacement therapy. XII∗ indicates mutated factor XII, resulting in increased susceptibility to activation by plasmin. PAI-2∗ indicates mutated plasminogen activator inhibitor, resulting in impaired inhibition of plasminogen activation into plasmin. Angiopoietin-1∗ indicates mutation of angiopoietin-1, resulting in impaired binding to its receptor (TIE2) on endothelial cells, which results in loss of vascular integrity. X indicates how angiotensin converting enzyme inhibitors (ACEI) impair bradykinin degradation. T indicates sites in the bradykinin generation pathway that are being targeted for therapy; available therapies are denoted in red; therapies in development are denoted in blue. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, 1810-1812DOI: (10.1016/j.jaip.2018.07.006) Copyright © 2018 Terms and Conditions