Overview. 5 Things You Need to Know About Statin Selection in Patients With HIV Infection.

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Presentation transcript:

5 Things You Need to Know About Statin Selection in Patients With HIV Infection

Overview

Increase in Proportionate CVD Mortality Rates in the HIV-Infected Population Since 1999, While Declining in Others

Why Has CVD Mortality Increased Among HIV-Infected Persons?

Assessment of CVD Risk in Patients With HIV Infection

Viral and ART Factors Contribute to Increased VLDL and Decreased HDL Levels

Importance of Statins in Patients With HIV Infection: Beyond LDL-C Reduction?

Role for Statins in Patients With HIV Infection

Mean Changes in Blood Lipids for 50 Seroconverters Initiating HAART

Contemporary ART: More Lipid Neutral

Assessment of CV Risk in the HIV-Infected Patient

Atorvastatin Effects on ASCVD Progression in HIV Infection Reduced Plaque Progression vs Placebo

Rosuvastatin Effects on CCA-IMT in HIV Infection: Reduced Carotid IMT Progression vs Placebo -- SATURN Trial

Use of Statins With Protease Inhibitors

Lifestyle and Pharmacologic Modification of Nonlipid CVD Risk Factors

REPRIEVE Trial Design

REPRIEVE Trial Hypotheses

Why Pitavastatin in REPRIEVE?

Concluding Remarks

Abbreviations

Abbreviations (cont)