Imiquimod 5% cream for treatment of HIV-negative Kaposi's sarcoma skin lesions: A phase I to II, open-label trial in 17 patients Noël Emile Célestin.

Slides:

Advertisements

Similar presentations

Tianyou Wang, MD, Xiaoxi Lin, MD, PhD, Yunbo Jin, MD, PhD, Xi Yang, MD

Advertisements

Secukinumab sustains early patient-reported outcome benefits through 1 year: Results from 2 phase III randomized placebo-controlled clinical trials comparing.

Topically applied ascorbic acid solution for the treatment of basal cell carcinoma (BCC) Péter Holló, MD, PhD, Hajnalka Jókai, MD, PhD, Judit Hársing,

Clavi syphilitici–an unusual presentation of syphilis

Optimal time to provide skin cancer and photoprotection education to pediatric solid organ transplant recipients Lily Chen, BA, Feng Gao, MD, PhD, MPH,

Lauren Kwa, BA, Jonathan I. Silverberg, MD, PhD, MPH

Striking leflunomide efficacy against refractory cutaneous sarcoidosis

Yul W. Yang, MD, PhD, David J. DiCaudo, MD

Accuracy of biopsy sampling for subtyping basal cell carcinoma

Allison Hanlon, MD, PhD, June Kim, MD, David J. Leffell, MD

Daniel S. Winchester, MD, Thomas L. Hocker, MD, Randall K. Roenigk, MD

Image registration of sequential transparent photographs to localize and detect new versus recurrent tumors in dermatologic and Mohs micrographic surgery

Aggressive cutaneous infection with Mycobacterium marinum in two patients receiving anti–tumor necrosis factor-alfa agents Julie Caron, MD, Carine Michot,

Tianyou Wang, MD, Xiaoxi Lin, MD, PhD, Yunbo Jin, MD, PhD, Xi Yang, MD

Baldness reversed by chemotherapy

Efficacy of simvastatin in plaque psoriasis: A pilot study

The diagnostic accuracy of in vivo confocal microscopy in clinical practice Danielle Giambrone, BS, Mahin Alamgir, MD, Aisha Masud, BS, Tara Bronsnick,

Elana Putterman, BS, Leslie Castelo-Soccio, MD, PhD

Sarah Sung, MD, Alexa B. Kimball, MD, MPH

Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the treatment of patients with moderate to.

Volume 2, Issue 1, Pages (January 2016)

Two randomized, double-blind, placebo-controlled studies of fluticasone propionate lotion 0.05% for the treatment of atopic dermatitis in subjects from.

The impact of secukinumab treatment on the prevalence of human papillomavirus in patients with psoriasis: A pilot study Hsien-Yi Chiu, MD, Tsen-Fang.

JAK inhibitors in dermatology: The promise of a new drug class

Khanh P. Thieu, BS, Harley A. Haynes, MD

Effect of appearance-based education compared with health-based education on sunscreen use and knowledge: A randomized controlled trial William Tuong,

Pharmacy costs of specialty medications for plaque psoriasis in the United States Eric J. Yang, BS, Kristen M. Beck, MD, Sahil Sekhon, MD, Tina Bhutani,

A pilot trial of treprostinil for the treatment and prevention of digital ulcers in patients with systemic sclerosis Lorinda Chung, MD, David Fiorentino,

Pilot study of a skin cancer education curriculum for medical students

Applying for dermatology residency is difficult and expensive

Reply to: “Comment on ‘Activation of melanocytes in idiopathic guttate hypomelanosis after 5-fluorouracil infusion using a tattoo machine: Preliminary.

Clinical and photographic assessment of lichen planopilaris treatment efficacy Aline Donati, MD, Philipe Assouly, MD, Bruno Matard, MD, Corinne Jouanique,

Google search trends for tanning salons: Temporal patterns indicate peak interest in mid spring Derek D. Reed, PhD, BCBA-D Journal of the American Academy.

A survey-based study on nail examinations at an American Academy of Dermatology free skin cancer screening Dayoung Ko, BS, Shari R. Lipner, MD, PhD

Loss of efficacy of secukinumab for psoriasis at 24 to 32 weeks

Topical calcipotriol before ablative fractional laser-assisted photodynamic therapy enhances treatment outcomes for actinic keratosis in Fitzpatrick grades.

Infectious rash after riding elephants

Lenalidomide in treatment-refractory cutaneous lupus erythematosus: Efficacy and safety in a 52-week trial Lauren Okon, MD, Misha Rosenbach, MD, Michael.

Gwanghyun Jo, MD, Je-Ho Mun, MD, PhD

Treatment of anal intraepithelial neoplasia in patients with acquired HIV with imiquimod 5% cream* Alexander Kreuter, MD, Bettina Hochdorfer, MD, Markus.

Lip edema Journal of the American Academy of Dermatology

Lip and oral mucosal lesions in 100 renal transplant recipients

Isotretinoin for high-grade or refractory epidermal growth factor receptor inhibitor-related acneiform papulopustular eruptions Herbert C. Chiang, MD,

Olga Vornicova, MD, Gil Bar-Sela, MD JAAD Case Reports

Pooja H. Rambhia, BA, Ivan J. Stojanov, DMD, Joshua Arbesman, MD

Medicaid acceptance among pediatric dermatologists

Penile calciphylaxis Journal of the American Academy of Dermatology

Christopher T. Cassetty, MD, Andrew F. Alexis, MD, MPH, Jerome L

Modification of the nail psoriasis severity index

Tofacitinib therapy for children with severe alopecia areata

Jose Fernández-Vozmediano, PhD, Jose Armario-Hita, MD

Michelle A. Pipitone, MD, Brian Adams, MD, MPH, Anita Sheth, MD, T

A simple algorithm for evaluating dermatologic disease in critically ill patients: A study based on retrospective review of medical intensive care unit.

An open-label study evaluating the efficacy and tolerability of alefacept for the treatment of scalp psoriasis James Krell, MD, FAAD, Candi Nelson, BS,

Eyebrow transplantation: Alternative body sites as a donor source

Recurrence of nevus depigmentosus after an autologous epidermal graft

Gaps in pain management in dermatology: A needs assessment from Canada

A grayscale photograph with high dynamic range taken under a Wood's lamp for better recognition of vitiligo lesions Jung Min Bae, MD, PhD, Tae Young.

Classification of facial psoriasis based on the distributions of facial lesions Seung Man Woo, MD, Jung Won Choi, MD, Hyun Sun Yoon, MD, Seong Jin Jo,

Numerous hyperpigmented macules of the oral mucosa

Brittany G. Craiglow, MD, Brett A. King, MD, PhD

Randomized study of topical tacrolimus ointment as possible treatment for resistant idiopathic pruritus ani Erwin Suys, MD Journal of the American Academy.

“Boot foot” with pseudomonas colonization

Apremilast, an oral phosphodiesterase-4 inhibitor, in the treatment of palmoplantar psoriasis: Results of a pooled analysis from phase II PSOR-005 and.

Topically applied ascorbic acid solution for the treatment of basal cell carcinoma (BCC) Péter Holló, MD, PhD, Hajnalka Jókai, MD, PhD, Judit Hársing,

Orit Kaidar-Person, MD, Ayelet Eran, MD, Gil Bar-Sela, MD

Global epidemiology and clinical spectrum of rosacea, highlighting skin of color: Review and clinical practice experience Andrew F. Alexis, MD, MPH,

Reporting of harm and safety results in randomized controlled trials published in 5 dermatology journals Cynthia Haddad, PharmD, MSc, Odette Berline.

Gram-negative folliculitis caused by Morganella morganii

Stuart M. Goldsmith, MD, Armand B. Cognetta, MD

Presentation transcript:

Imiquimod 5% cream for treatment of HIV-negative Kaposi's sarcoma skin lesions: A phase I to II, open-label trial in 17 patients Noël Emile Célestin Schartz, MD, PhD, Sylvie Chevret, MD, PhD, Carolina Paz, MD, Delphine Kerob, MD, Olivier Verola, MD, Patrice Morel, MD, Céleste Lebbé, MD, PhD Journal of the American Academy of Dermatology Volume 58, Issue 4, Pages 585-591 (April 2008) DOI: 10.1016/j.jaad.2007.11.005 Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 At 36 weeks, 5 (29%) of 17 patients achieved overall clinical response (complete and partial) evaluated on basis of tumor area (A) and 11 (65%) achieved overall clinical response on basis of infiltration score (B). Journal of the American Academy of Dermatology 2008 58, 585-591DOI: (10.1016/j.jaad.2007.11.005) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 At 36 weeks, 22 (24%) of 90 lesions achieved overall clinical response (complete and partial) evaluated on basis of tumor area (A) and 48 (53%) achieved overall clinical response on basis of infiltration score (B). Journal of the American Academy of Dermatology 2008 58, 585-591DOI: (10.1016/j.jaad.2007.11.005) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Biopsy-proven nodular Kaposi's sarcoma lesions of thumb in Caucasian man before (A) and after (B) 24 weeks of imiquimod treatment. Journal of the American Academy of Dermatology 2008 58, 585-591DOI: (10.1016/j.jaad.2007.11.005) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Papular Kaposi's sarcoma lesions of thenar eminence in black man before (A) and after (B) 24 weeks of imiquimod treatment. Journal of the American Academy of Dermatology 2008 58, 585-591DOI: (10.1016/j.jaad.2007.11.005) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 5 Multiple papular Kaposi's sarcoma lesions on ankle of Caucasian woman before (A) and after (B) 24 weeks of imiquimod treatment. Journal of the American Academy of Dermatology 2008 58, 585-591DOI: (10.1016/j.jaad.2007.11.005) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions