Volume 18, Issue 2, Pages (April 2011)

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Volume 18, Issue 2, Pages 137-142 (April 2011) Amlodipine treatment decreases plasma and carotid artery tissue levels of endothelin-1 in atherosclerotic rabbits Bahman Rashidi, Mostafa Mohammadi, Fariba Mirzaei, Reza Badalzadeh, Parham Reisi Pathophysiology Volume 18, Issue 2, Pages 137-142 (April 2011) DOI: 10.1016/j.pathophys.2010.05.003 Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Standard hematoxylin–eosin (H&E) staining of carotid artery for the evaluation of the atherosclerotic lesions in 2% high-cholesterol diet group. No lesions were observed in control group. Consumption of 2% high-cholesterol diet induced atherosclerotic lesions that observed as enhancement of endothelial cells diameter with accumulation of lipid droplets under endothelial cells that are seen as yellowish white (can seen in the tips of arrows). I: intima; M: media; A: adventitia. 660×. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of the article.) Pathophysiology 2011 18, 137-142DOI: (10.1016/j.pathophys.2010.05.003) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Standard hematoxylin–eosin (H&E) staining of carotid artery for the evaluation of the atherosclerotic lesions in 2% high-cholesterol diet receiving amlodipine group. By amlodipine treatment these effects were observed: diameter of endothelial layer is reduced, and no or minimum accumulation of lipid droplets is seen under endothelial cells. I: intima; M: media; A: adventitia; EC: endothelial cell. 660×. Pathophysiology 2011 18, 137-142DOI: (10.1016/j.pathophys.2010.05.003) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions