Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: A comprehensive propensity-matched.

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Presentation transcript:

Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: A comprehensive propensity-matched analysis Laila Al-Shaar, MS, MPH, Thomas A. Schwann, MD, Ameer Kabour, MD, Robert H. Habib, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 148, Issue 5, Pages 1860-1868.e2 (November 2014) DOI: 10.1016/j.jtcvs.2014.05.020 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Comparison of unadjusted cumulative late Kaplan-Meier survival for coronary artery bypass grafting (CABG) patients grouped according to, left, postoperative atrial fibrillation (POAF) status and, right, then subcategorized according to the presence of other postoperative complications, including no POAF and no complications (no-AF group; n = 5094), isolated POAF and no other complication (AF group, n = 1211), postoperative complications other than POAF (no-AF/C group, n = 832), and POAF plus other postoperative complications (AF/C group, n = 473). AF, Atrial fibrillation. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1860-1868.e2DOI: (10.1016/j.jtcvs.2014.05.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Top, Comparison of cumulative 18-year Kaplan-Meier mortality after uncomplicated coronary artery bypass grafting (CABG) in propensity matched patients without postoperative atrial fibrillation (POAF; no-AF group) versus patients with isolated POAF (AF group). Left, AF versus single-match no-AF (n = 1196 matched pairs; 1 AF, 1 no-AF); Middle, AF versus double-match no-AF (n = 993 matched triplets; 1 AF, 2 no-AF); and Right, AF versus triple-match no-AF (n = 719 matched quadruplets; 1 AF, 3 no-AF). Bars represent the standard error of the cumulative mortality. Bottom, Tabular data represent the number of patients at risk at different measurement points. AF, Atrial fibrillation. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1860-1868.e2DOI: (10.1016/j.jtcvs.2014.05.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Ratio of AF to no-AF cumulative death hazard as a function of time after hospital discharge. Data in parentheses are 95% confidence intervals. HRt, Time-segmented HR; HRt(0-1), HRt at 0 to 1 years postoperatively; HRt(1-6), HRt at 1 to 6 years postoperatively; HRt(6-17), HRt at 6 to 17 years postoperatively; CABG, coronary artery bypass grafting. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 1860-1868.e2DOI: (10.1016/j.jtcvs.2014.05.020) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions