Higher β-HCG concentrations and higher birthweights ensue from single vitrified embryo transfers Kevin N. Keane, Kamarul Bahyah Mustafa, Peter Hinchliffe,

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Presentation transcript:

Higher β-HCG concentrations and higher birthweights ensue from single vitrified embryo transfers Kevin N. Keane, Kamarul Bahyah Mustafa, Peter Hinchliffe, Jason Conceicao, John L. Yovich Reproductive BioMedicine Online Volume 33, Issue 2, Pages 149-160 (August 2016) DOI: 10.1016/j.rbmo.2016.04.014 Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Flow chart of SET treatment cycles selection for pregnancy test β-HCG value and singleton live-birth outcome following IVF-ET versus FET. FET = frozen embryo transfer; HCG = human chorionic gonadotrophin; IVF-ET = IVF fresh embryo transfer; TOP = termination of pregnancy. Reproductive BioMedicine Online 2016 33, 149-160DOI: (10.1016/j.rbmo.2016.04.014) Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Overview of luteal day estimation and day 14 pregnancy dating for the different treatment cycles, showing days when luteal phase HCG support injections were applied. FET = frozen embryo transfer; HRT = hormone replacement therapy; IVF-ET = IVF fresh embryo transfer; LDS = low-dose stimulation; NAT = natural; rHCG = recombinant human chorionic gonadotrophin; TVOA = transvaginal oocyte aspiration. Reproductive BioMedicine Online 2016 33, 149-160DOI: (10.1016/j.rbmo.2016.04.014) Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Mean β-HCG concentrations and birthweights for IVF-ET and FET cycles when grouped according to infant gender (A and B), transferred embryo development stage (C and D) and embryo quality (E and F), respectively. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. FET = frozen embryo transfer; HCG = human chorionic gonadotrophin; IVF-ET = IVF fresh embryo transfer. Reproductive BioMedicine Online 2016 33, 149-160DOI: (10.1016/j.rbmo.2016.04.014) Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions

Figure 4 Mean β-HCG concentrations and birthweights for IVF-ET and FET cycles when tested at luteal day 19 only and grouped according to infant gender (A and B), transferred embryo development stage (C and D) and embryo quality (E and F), respectively. * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001. FET = frozen embryo transfer; HCG = human chorionic gonadotrophin; IVF-ET = IVF fresh embryo transfer. Reproductive BioMedicine Online 2016 33, 149-160DOI: (10.1016/j.rbmo.2016.04.014) Copyright © 2016 Reproductive Healthcare Ltd. Terms and Conditions