Probiotics in prevention of IgE-associated eczema: A double-blind, randomized, placebo-controlled trial Thomas R. Abrahamsson, MD, Ted Jakobsson, MD,

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Presentation transcript:

Probiotics in prevention of IgE-associated eczema: A double-blind, randomized, placebo-controlled trial Thomas R. Abrahamsson, MD, Ted Jakobsson, MD, Malin Fagerås Böttcher, PhD, Mats Fredrikson, PhD, Maria C. Jenmalm, PhD, Bengt Björkstén, MD, PhD, Göran Oldaeus, MD, PhD Journal of Allergy and Clinical Immunology Volume 119, Issue 5, Pages 1174-1180 (May 2007) DOI: 10.1016/j.jaci.2007.01.007 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Participation rate and reason for discontinuation. Families were excluded if their baby was admitted to the neonatal ward during the first week of life or if they had a poor compliance. A total of 16 of 19 families declining participation gave no reason, whereas 3 (2 in the L reuteri group) did so because of abdominal discomfort/colic. Journal of Allergy and Clinical Immunology 2007 119, 1174-1180DOI: (10.1016/j.jaci.2007.01.007) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Prevalence of any eczema (solid lines) and IgE-associated eczema (hatched lines) during the first 24 months of life in infants receiving daily oral supplementation of L reuteri (closed symbols) or placebo (open symbols) during the first 12 months of life. ∗P = .02 with χ2 test. Journal of Allergy and Clinical Immunology 2007 119, 1174-1180DOI: (10.1016/j.jaci.2007.01.007) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions