Early and Intensive T2D Management:

Slides:



Advertisements
Similar presentations
Case-Based Examination of Treatment Options in Type 2 Diabetes Management.
Advertisements

Taieb V, et al. Value Health Nov;18(7):A598.
Cardiovascular Outcomes Trials in Diabetes: The Truth, the Whole Truth, and Nothing But the Truth.
Current Dyslipidemia Management Guidelines Residual Risk.
CV Risk Management in Diabetes: A Mandate for GLP-1 Receptor Agonists?
An Update on Oral Prostanoids: Advancing Care for PAH?
SGLT2 Inhibitors: What Do the Data Mean for My Patients?
Updates on Emerging GLP-1 Receptor Agonists
Updates on CVOT Data and Clinical Comparisons That Matter
The Nurse View.
SGLT2 Inhibitors and Their Clinical Impact:
Global Projections for Diabetes:
Expert Panelists. Emerging CV Outcomes Trial Results: What Do They Mean for T2D Management?
Patient Case Discussions in T2D: What Intensification Plan Is Best?
Moderate-Intensity Statins for Dyslipidemia: How to Treat Today?
What Comes Second?.
Updates on Outcomes for Novel T2D Therapies
Program Goals. Consulting the Experts: Prandial Insulin or a GLP-1 Receptor Agonist as Add-On to Basal Insulin.
SGLT2 Inhibitors in Phase 3 Trials
Clinical Advances in Type 2 Diabetes and Cardiovascular Risk
Updates Abound.
SGLT2 Inhibitors in the Modern Era: Why and Where?
Emerging CVOT Data and Clinical Application
How Effective Is Fixed-Dose Combination Therapy in T2D and Where Does It Fit?
Clinical Application of New CV Outcomes Data
GLP-1 Receptor Agonists: How Early Is Appropriate?
T2DM and CV Outcomes Trials: A Deep Dive!
A Deep Dive Into CVOTs.
Assessing the State of Statin Therapy
Should SGLT2 Inhibitors Be the Primary Agents for CV Risk Reduction in T2DM?
SGLT2 inhibitors, Now Part of the Cardiology Toolkit for Comprehensive CV Risk Management.
A New Chapter for CV Risk Management in Diabetes - Challenges & Opportunities.
Evaluating LDL-C Recommendations
PCP View: ACC/AHA Guidelines: Role of Moderate Intensity Statins
Case Study Role of DPP-4 Inhibitors
Tackling CV Risk in T2DM.
2008 FDA Guidance. Working as a Team for Cardiovascular Risk Reduction in Patients With T2D.
Rheumatoid Arthritis 2015 Guidelines What's New? What's Different?
Breaking Down the CVOTs
Antihyperglycemic therapy in type 2 diabetes: general recommendations
Novel Approaches in T1D Management
Injectable Options as Add-Ons to Basal Insulin: Targeting PPG in Type 2 Diabetes Patients.
Heart Failure Hospitalization Risks with DPP-IV Inhibitors: Myth or Reality?
New Horizons in Adjunctive Type 1 Diabetes Management With SGLT Inhibitors.
T2DM, CV Safety, and Efficacy: DPP-4 Inhibitors in focus
LEADER One Year On.
Use of Combination of Saxagliptin/ Dapagliflozin in Patients With Poorly Controlled Diabetes on Metformin.
Learning Objectives Metabolic Abnormalities Associated With T2D.
Novel Approaches to T1D Management
Antihyperglycemic Therapy
Optimizing Insulin Therapy in Primary Care: Basal Plus Incretin Combinations.
CAD and HF Often Coexist
CV Risk Reduction with Diabetes Drugs -- Should Cardiologists or Diabetologists Take the Lead?
The Role of the Kidney in Glucose Control
Case Challenges: Early and Intensive Type 2 Diabetes Treatment With Modern Agents.
Oral Combination Therapy for T2D
Dual SGLT1/SGLT2 Inhibition in T1D
Changes in A1C (A), body weight (B), and systolic blood pressure (C) with canagliflozin in combination with incretin-based therapies. *In the dose-advancement.
Add-On Therapy to Insulin in T1DM Management
Patient Selection for Modern T2D Agents
Improving Overall Health
2015 EASD In Review: CV Risk management in t2dm
Checkpoint Inhibitors in First-Line Advanced NSCLC
Emerging Combination Injectable Therapy A New Era in Diabetes Care
Type 1 Diabetes: Expanding Options for Adjunctive Oral Therapy With SGLT Inhibitors.
Should SGLT2 Inhibitors Be the Primary Agents for CV Risk Reduction in T2DM?
What's New in Oral Combination Therapy for Type 2 Diabetes?
BRIDGING CVD AND T2DM: LESSONS LEARNED FROM OUTCOME TRIALS
Risk Stratification of Patients With Type 2 Diabetes: An Interpretation of the Latest Treatment Guidelines.
Top Tips in Evidence-Based Care for HFrEF
Presentation transcript:

Early and Intensive T2D Management:

Program Goals

TECOS Sitagliptin in Patients With T2D and Established CVD

FDA Drug Safety Communication

Guidelines: Initial Combination Therapy Recommendations

Fixed-Dose Combination Therapy Rationale for Use

Dapagliflozin/Saxagliptin Add-On to MET

Combination Therapy With DPP-4 Inhibitors: Meta-Analysis

Combination Therapy With SGLT2 Inhibitors Add-On to MET -- Meta-Analysis

SGLT2 Inhibitor + GLP-1 Receptor Agonist Combo Ongoing Trials

Initial Combination Therapy: CANA + MET XR in Drug-Naïve Patients Study Design

Initial Combination Therapy: CANA + MET XR in Drug-Naïve Patients Mean Change in HbA1c

Initial Combination Therapy: CANA + MET XR in Drug-Naïve Patients Proportion of Patients With HbA1c < 7.0%

Triple Therapy: DAPA Add-on to SAXA Plus MET Study Design

Triple Therapy: DAPA Add-on to SAXA + MET Distribution of HbA1c in Patients at Week 2

Fixed-Dose Combination Potential Benefits

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)

References (cont)

References (cont)

References (cont)