TB Determined: Tuberculous Osteomyelitis

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TB Determined: Tuberculous Osteomyelitis Dan Lebowitz, MD, Line Wolter, MD, Christiane Zenklusen, MD, Amine Chouiter, MD, Raffaele Malinverni, MD The American Journal of Medicine Volume 127, Issue 3, Pages 198-201 (March 2014) DOI: 10.1016/j.amjmed.2013.12.001 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Total-body computed tomography (CT) revealed heterogeneous hyperdense lesions of the vertebral bodies of T11, L1, and L2. The American Journal of Medicine 2014 127, 198-201DOI: (10.1016/j.amjmed.2013.12.001) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 2 Lesions found in the vertebral bodies were enhanced by contrast medium (A), hypointense in T1-weighted images (B) and hyperintense in T2-weighted images (C); no cortical disruption, intervertebral disk space involvement, or paravertebral or epidural abscesses were seen. The American Journal of Medicine 2014 127, 198-201DOI: (10.1016/j.amjmed.2013.12.001) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 3 In this image from 18F-fluorodeoxyglucose positron emission tomography-CT (FDG-PET-CT), diffuse increased 18F-FDG uptake was evident in the ribs, sternum, cervicothoracolumbar spine, sacrum, and symphysis pubis; the maximal standardized-uptake-value (SUVmax) was 18. The American Journal of Medicine 2014 127, 198-201DOI: (10.1016/j.amjmed.2013.12.001) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 4 This necrotizing granulomatous inflammatory infiltrate was discovered during a biopsy of L1, the most hypermetabolic vertebra (hematoxylin and eosin, 20x). The American Journal of Medicine 2014 127, 198-201DOI: (10.1016/j.amjmed.2013.12.001) Copyright © 2014 Elsevier Inc. Terms and Conditions