Health-related Quality of Life of Bone Marrow versus Peripheral Blood Stem Cell Donors: A Prespecified Subgroup Analysis from a Phase III RCT—BMTCTN Protocol.

Slides:



Advertisements
Similar presentations
Alexander H. Schmidt, Thilo Mengling, Camila J
Advertisements

Related PBSC Donors Age >60 Have High Rates of Baseline and Donation-Related Pain and Slow Recovery: First Report from the Related Donor Safety Study.
Michael A. Pulsipher, Christina Peters, Ching-Hon Pui 
Mohamed A. Kharfan-Dabaja, Claudio Anasetti, Edgardo S. Santos 
Improvement of Disease Status Determination and Documentation Pre- and Post- Transplant  Michelle Bycko, Crystal Gazaway, Jennifer Holter Chakrabarty,
How to Treat MDS without Stem Cell Transplantation
Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program by Michael.
The Effect of the Composition of Unrelated Donor Bone Marrow and Peripheral Blood Progenitor Cell Grafts on Transplantation Outcomes  Nancy H. Collins,
Vaccination of Children following Allogeneic Stem Cell Transplantation
Randomized Phase III Trial of Pegfilgrastim versus Filgrastim after Autologus Peripheral Blood Stem Cell Transplantation  Aaron Gerds, Mary Fox-Geiman,
Sympathectomy Protects Denervated Skin from Graft-Versus-Host Disease
Predictive Value of Pre-Transplant PET/CT Scan before Autologous Stem Cell Transplant in Mantle Cell Lymphoma  Brian Hess, MD, Kathryn Trinkaus, Ph.D.,
Generic Immunosuppressants in Hematopoietic Cell Transplantation
NCI, NHLBI/PBMTC First International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Endocrine Challenges—Thyroid Dysfunction,
NCI, NHLBI/PBMTC First International Conference on Late Effects After Pediatric Hematopoietic Cell Transplantation: Persistent Immune Deficiency in Pediatric.
Pain, Donation-Related Symptoms and the Trajectory of Recovery in Children after Bone Marrow (BM) Donation Are Influenced By Age (Pre vs. Post-Puberty)
Related PBSC Donors Experience Higher Levels of Pain and Donation-Related Symptoms and Less Complete Rates of Recovery Compared to Unrelated Donors:
Sabina Kersting, Leo F. Verdonck 
CD34-Selected, T Cell Depleted Haploidentical Donor Peripheral Blood Stem Cell (PBSC) Transplantation in Children with Malignant (MD) and Non-Malignant.
Peripheral Blood Grafts from Unrelated Donors Are Associated with Increased Acute and Chronic Graft-versus-Host Disease without Improved Survival  Mary.
Caroline F. Morrison, Donna M
Jane Kempenich, Kelly Buck, John Hermanson, Jason Dehn, MPH 
Decision Analysis of Peripheral Blood versus Bone Marrow Hematopoietic Stem Cells for Allogeneic Hematopoietic Cell Transplantation  Joseph Pidala, Claudio.
Symptom Distress Predicts Long-Term Health and Well-Being in Allogeneic Stem Cell Transplantation Survivors  Margaret F. Bevans, Sandra A. Mitchell, John.
Recent Decrease in Acute Graft-versus-Host Disease in Children with Leukemia Receiving Unrelated Donor Bone Marrow Transplants  Stella M. Davies, Dan.
More Infections with Transplantation of Bone Marrow, Versus Peripheral-Blood Stem Cells, from Unrelated Donors  Jo-Anne H. Young, MD, Brent R. Logan,
Jo-Anne H. Young, Brent R. Logan, Juan Wu, John R. Wingard, Daniel J
Motivations, Experiences, and Perspectives of Bone Marrow and Peripheral Blood Stem Cell Donors: Thematic Synthesis of Qualitative Studies  Maria C. Garcia,
High Rate of Long Term Complete Remission for Patients with Chronic Lymphocytic Leukemia (CLL) Who Relapse after Allogeneic Stem Cell Transplantation.
A Process to Facilitate Decision Making in Pediatric Stem Cell Transplantation: The Individualized Care Planning and Coordination Model  Justin N. Baker,
Controversies in Lymphoma: The Role of Hematopoietic Cell Transplantation for Mantle Cell Lymphoma and Peripheral T Cell Lymphoma  Peter Dreger, Ginna.
Significant Improvement in Survival after Unrelated Donor Hematopoietic Cell Transplantation in the Recent Era  Navneet S. Majhail, Pintip Chitphakdithai,
John R. Wingard, M. D. , Alan K. Leahigh, Dennis Confer, M. D
Biology of Blood and Marrow Transplantation
A Retrospective Analysis of Bloodstream Infections in Pediatric Allogeneic Stem Cell Transplant Recipients: The Role of Central Venous Catheters and Mucosal.
B Cells and Transplantation: An Educational Resource
Allogeneic Hematopoietic Stem Cell Transplantation in Adult Acute Lymphocytic Leukemia: Impact of Donor Source on Survival  Priya Kumar, Todd E. Defor,
Recovery of Unrelated Donors of Peripheral Blood Stem Cells versus Recovery of Unrelated Donors of Bone Marrow: A Prespecified Analysis from the Phase.
Pharmacokinetic Evaluation of the Drug Interaction between Intravenous Itraconazole and Intravenous Tacrolimus or Intravenous Cyclosporin A in Allogeneic.
Employment Status as an Indicator of Recovery and Function One Year after Hematopoietic Stem Cell Transplantation  Eleshia J. Morrison, Shawna L. Ehlers,
High-Resolution Match Rate of 7/8 and 9/10 or Better for the Be The Match Unrelated Donor Registry  Kelly Buck, Kim Wadsworth, Michelle Setterholm, Martin.
Predonation Health-Related Quality of Life Scores Predict Time to Recovery in Hematopoietic Stem Cell Donors  Annelies Billen, J. Alejandro Madrigal,
Allogeneic Stem Cell Transplantation for Aplastic Anemia
NCI, NHLBI/PBMTC First International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Health-Related Quality of Life, Functional,
Comparative Analysis: Trend of Infectious Complications in Cord Blood (CB) Versus Peripheral Blood (PB) and Bone Marrow (BM) Stem Cell Transplant (SCT)
Race and Ethnicity Influences Collection of Granulocyte Colony–Stimulating Factor– Mobilized Peripheral Blood Progenitor Cells from Unrelated Donors, a.
Regression Models for Hazard Rates Versus Cumulative Incidence Probabilities in Hematopoietic Cell Transplantation Data  Brent R. Logan, Mei-Jie Zhang,
ASBMT and CBMTG Release Choosing Wisely BMT Recommendations
Gerard Socié, K. Scott Baker, Smita Bhatia 
What is quality in a transplant program?
Redesigning Care to Lower Episode Costs in Bone Marrow Transplantation
Richard Mitchell, John E. Wagner, Claudio G
Chimeric Antigen Receptor–Modified T Cells: Clinical Translation in Stem Cell Transplantation and Beyond  Stanley R. Riddell, Michael C. Jensen, Carl.
Improved Outcome for Peripheral Blood Stem Cell Transplantation for Advanced Primary Myelodysplastic Syndrome  Scott R. Solomon, Bipin N. Savani, Richard.
Unrelated Donor Hematopoietic Cell Transplantation: Factors Associated with a Better HLA Match  Jason Dehn, Mukta Arora, Stephen Spellman, Michelle Setterholm,
Blood and Marrow Transplant Handbook
Therapeutic Immunosuppression Concentrations on Day 0 and the Development of Acute Graft Versus Host Disease (GVHD) in Hematopoietic Stem Cell Transplantation.
Young Female Donors Do Not Increase the Risk of Graft-versus-Host Disease or Impact Overall Outcomes in Pediatric HLA-Matched Sibling Hematopoietic Stem.
Mammen Chandy  Biology of Blood and Marrow Transplantation 
Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: results of a prospective trial from the National Marrow Donor Program.
Treatment versus Transplant for Challenging Hematologic Disorders
IL-8 Levels Early after Bone Marrow Transplant are Associated with Later Complications of Stem Cell Transplantation  Nikhil Dole, Nathan Luebbering, Nicholas.
Classification of HLA-Matching for Retrospective Analysis of Unrelated Donor Transplantation: Revised Definitions to Predict Survival  Daniel Weisdorf,
Mary Eapen  Biology of Blood and Marrow Transplantation 
Older Age But Not Donor Health Impairs Allogeneic Granulocyte Colony-Stimulating Factor (G-CSF) Peripheral Blood Stem Cell Mobilization  Elie Richa, Mona.
In Memoriam: E. Donnall Thomas
Optimal Donor Selection: Beyond HLA
Donald R. Dengel, Aaron S. Kelly, Lei Zhang, Qi Wang, James S
Radiation Disasters: Role of the BMT Team
Donor Experiences of Second Marrow or Peripheral Blood Stem Cell Collection Mirror the First, but CD34+ Yields Are Less  David F. Stroncek, Bronwen E.
Presentation transcript:

Health-related Quality of Life of Bone Marrow versus Peripheral Blood Stem Cell Donors: A Prespecified Subgroup Analysis from a Phase III RCT—BMTCTN Protocol 0201  Galen E. Switzer, Jessica G. Bruce, Donna Harrington, Michael Haagenson, Rebecca Drexler, Amy Foley, Dennis Confer, Michelle Bishop, Paolo Anderlini, Scott Rowley, Susan F. Leitman, Claudio Anasetti, John R. Wingard  Biology of Blood and Marrow Transplantation  Volume 20, Issue 1, Pages 118-127 (January 2014) DOI: 10.1016/j.bbmt.2013.10.024 Copyright © 2014 Terms and Conditions

Figure 1 Longitudinal pre- and postdonation physical and mental states for bone marrow and peripheral blood stem cell donors. Physical and mental health summary scores were assessed with the Short Form–8; higher scores indicate better physical or mental health. Biology of Blood and Marrow Transplantation 2014 20, 118-127DOI: (10.1016/j.bbmt.2013.10.024) Copyright © 2014 Terms and Conditions

Figure 2 Time to full recovery by product donated. Biology of Blood and Marrow Transplantation 2014 20, 118-127DOI: (10.1016/j.bbmt.2013.10.024) Copyright © 2014 Terms and Conditions