Breaking Down the CVOTs

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Presentation transcript:

Breaking Down the CVOTs

Why CVOTs and What Do They Mean?

Increased Risk of Mortality and CVD in T2D

Completed and Ongoing CVOTs Study Populations

Published CVOTs Different Populations

Published DPP-4 Inhibitor CVOTs Comparison of Results

GLP-1 RA CVOTs Comparison of Results

SGLT2 Inhibitor CVOT Results From EMPA-REG OUTCOME

CANVAS Study Population

EMPA-REG OUTCOME and CANVAS CVOTs Comparison of Results

CANVAS Canagliflozin Is Renoprotective

Implications for Clinical Practice RCTs vs Real World

CANVAS: Safety of Canagliflozin

Closing Comments

Abbreviations

Abbreviations (cont)