Lipid Metabolism.

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Presentation transcript:

Lipid Metabolism

Lipid Metabolism

Lipid Metabolism

Lipid Metabolism Digestion - Hydrolysis Reaction

Lipid Metabolism

Lipid Metabolism

Fatty Acid Oxidation Initial Step: Requires an ATP to synthesize acetyl CoA with the fatty acid.

Beta Oxidation

Beta Oxidation

Beta Oxidation

Beta Oxidation

Beta Oxidation

Beta Oxidation

Beta Oxidation

Palmitic Acid Review

Palmitic Acid -ATP Synthesis Palmitic Acid is C-16 Initiating Step - requires 1 ATP (text says 2) Step 1 - FAD into e.t.c. = 2 ATP Step 3 - NAD+ into e.t.c. = 3 ATP Total ATP per turn of spiral = 5 ATP Example with Palmitic Acid = 16 carbons = 8 acetyl groups Number of turns of fatty acid spiral = 8-1 = 7 turns ATP from fatty acid spiral = 7 turns and 5 per turn = 35 ATP. NET ATP from Fatty Acid Spiral = 35 - 1 = 34 ATP

Palmitic Acid (C-16) -ATP Synthesis NET ATP - Fatty Acid Spiral = 35 - 1 = 34 ATP Review ATP - Citric Acid Cycle start with Acetyl CoA Step ATP produced 7 visible ATP 1 Step 4 (NAD+ to E.T.C.) 3 Step 6 (NAD+ to E.T.C.) 3 Step10 (NAD+ to E.T.C.) 3 Step 8 (FAD to E.T.C.) 2 NET 12 ATP per turn C.A.C. 8 Acetyl CoA = 8 turns C.A.C. 8 turns x 12 ATP/C.A.C. = 96 ATP GRAND TOTAL 130 ATP

Acetyl CoA

Ketone Bodies

Ketone Bodies

Blood Glucose and Glucosuria

Ketone Bodies

Lipogenesis